Table 1 In utero and first year of life exposures to air pollutants sources and their temporal sequence with asthma phenotypes in children of the EDEN mother-child cohort study
Period of life/Air pollutant and related sources | Corresponding questions | Temporal sequence of asthma phenotypes in relation to exposure | |
|---|---|---|---|
Exposure assessed in the first of life (at the period of the outcome) | In uteroexposure (preceding the outcome) | ||
In utero life | |||
Prenatal maternal smoking | 1. Did you smoke during the first trimester of pregnancy? | No | Yes |
2. Did you smoke during the second trimester of pregnancy? | |||
3. Did you smoke during the third trimester of pregnancy? | |||
Traffic-related air pollution | 1. Does your house located near a bus stop or a passageway of trucks? | No | Yes |
2. Does the cars often or continuously pass by your house? | |||
First year of life | |||
Heavy parental smoking in the last 12 months | 1. Did you smoke at present? | Yes | No |
2. An answer of “more than 20” to the question “How many cigarettes do you smoke every day?” | |||
Traffic-related air pollution in the last 12 months | 1. Do you live less than 200 meters away from a road with heavy traffic? | Yes | No |
2. Notably, Google Earth was used to check the validity of maternal reporting by taking into account a 200 m circular buffer and more than 10,000 vehicles per day (traffic volumes were provided by local authorities) using the home address as reference.. | |||
Dampness in the last 12 months | Are there any problems of dampness, moisture or condensation that have often, or permanently, existed in the house since the birth of the child? | Yes | No |
Visible moulds in the past 12 months | Are there any visible moulds that have often, or permanently, existed in the house of the child since the birth of the child? | Yes | No |
Bleaching agents in the past 12 months | Do you often clean with or use the bleaching agents in the presence of the child? | Yes | No |
House dust mites in the past 12 months | Has your child frequently been in contact with carpets, or glazing, or curtains? | Yes | No |
Contact with cats in the past 12 months | 1. Was there a new cat in your house and (or) did you let the cat enter the sleeping room of the child? | Yes | No |
2. Did your child contact with cats outside your house at least once per week? | |||
Contact with dogs in the past 12 months | 1. Was there a new dog in your house and (or) did you let the dog enter the sleeping room of the child? | Yes | No |
2. Did your child contact with dogs outside your house at least once per week? | |||
Type of domestic heating in the past 12 months | Which is your main type of heating in the house: gas, petroleum, wood or others? | Yes | No |