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Table 2 Predictors of non-adherence to TB medication (N = 3107)

From: Predictors of tuberculosis (TB) and antiretroviral (ARV) medication non-adherence in public primary care patients in South Africa: a cross sectional study

Socio-demographics

Crude OR (95% CI)

Adjusted OR (95% CI)a,b

Age 18–24

1.00

1.00

Age 25–34

0.76 (0.59–0.97)*

0.93 (0.65–1.32)

Age 35–44

0.77 (0.60–1.00)

1.00 (0.68–1.45)

Age 45 and older

0.80 (0.61–1.05)

0.65 (0.43–1.00)

Female

1.00

1.00

Male

1.26 (1.07–1.48)**

1.09 (0.86–1.38)

Grade 7 or less

1.00

1.00

Grade 8–11

0.88 (0.72–1.06)

1.07 (0.80–1.43)

Grade 12 or more

0.68 (0.55–0.85)***

0.76 (0.54–1.07)

Poverty low

1.00

1.00

Poverty medium

1.97 (1.62–2.410***

1.73 (1.34–2.24)***

Poverty high

4.01 (3.12–5.10)***

1.65 (1.14–2.39)**

Health variables

Perceived health status

Excellent/Very good

1.00

1.00

Good

0.36 (0.29–0.45)***

0.50 (0.37–0.67)***

Fair/Poor

0.24 (0.20–0.30)***

0.44 (0.32–0.60)***

TB retreatment patient

1.00

New TB patient

0.82 (0.67–1.00)

 

HIV positive

1.00

1.00

HIV negative

0.40 (0.34–0.48)***

0.44 (0.33–0.59)***

Chronic conditions

Zero

1.00

1.00

One

1.54 (1.23–1.93)***

1.86 (1.41–2.46)***

Two

1.84 (1.34–2.51)***

2.44 (1.68–3.56)***

Three or more

1.98 (1.34–2.92)***

2.37 (1.45–3.88)***

Severe psychological distress (K ≥ 30)

1.31 (1.09–1.57)**

0.94 (0.73–1.22)

Alcohol: low risk (AUDIT 0–7)

1.00

1.00

Medium (AUDIT 8–19)

1.74 (1.42–2.19)***

1.65 (1.23–2.29)***

High (AUDIT 20–40)

2.42 (1.76–3.32)***

3.06 (1.94–4.81***

Current tobacco use

2.09 (1.76–2.49)***

1.35 (1.04–1.75)*

On ART

0.70 (0.56–0.86)***

0.78 (0.60–1.03)

Partner HIV negative/unknown

1.00

1.00

Partner HIV positive

1.41 (1.16–1.70)***

1.43 (1.10–1.84)**

  1. *P < 0.05; ** P < 0.01; *** P < 0.001.
  2. aUsing “enter” LR selection of variables.
  3. bHosmer and Lemeshow Chi-square 7.68, df8, 0.466; Cox and Snell R2 0.11; Nagelkerke R2 0.16.