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Table 3 Disease specific standardized mortality ratios for HCV serological groups vs. BC population

From: Mortality among British Columbians testing for hepatitis C antibody

  

SNR (n=342,325)

MNR (n=73,476)

REAC (n=27,812)

SERO (n=2,408)

All HCV +ve (n=30,220)

ICD-10

Cause of death

SMR (95% CI)

SMR (95% CI)

SMR (95% CI)

SMR (95% CI)

SMR (95% CI)

A00-B99

Infection

1.57 (1.38 - 1.78)

4.36 (3.55 - 5.30)

31.51 (29.08 - 34.09)

32.09 (19.32 - 50.05)

31.53 (29.14 - 34.07)

C00-D48

Neoplasms

1.35 (1.31 - 1.40)

1.72 (1.59 - 1.87)

2.35 (2.14 - 2.59)

1.98 (0.73 - 4.31)

2.35 (2.13 - 2.58)

D50-D89

Blood/immune

1.82 (1.33 - 2.43)

5.18 (2.83 - 8.71)

7.91 (4.09 - 13.84)

36.40 (0.92 - 202.75)

8.41 (4.48 - 14.39)

E00-E90

Endocrine

1.82 (1.67 - 1.97)

5.29 (4.58 - 6.07)

2.07 (1.48 - 2.82)

3.21 (0.08 - 17.87)

2.09 (1.50 - 2.83)

F00-F99

Mental and behavioural

1.16 (1.02 - 1.31)

2.61 (1.99 - 3.37)

6.79 (5.43 - 8.37)

16.01 (4.35 - 40.98)

6.96 (5.60 - 8.55)

G00-G99

Nervous system

1.05 (0.95 - 1.17)

1.49 (1.11 - 1.95)

1.78 (1.21 - 2.53)

6.96 (0.84 - 25.11)

1.87 (1.29 - 2.62)

I00-I99

Circulatory system

1.42 (1.38 - 1.46)

2.22 (2.06 - 2.40)

2.21 (1.98 - 2.45)

6.04 (3.01 - 10.81)

2.25 (2.03 - 2.50)

J00-J99

Respiratory system

1.29 (1.22 - 1.37)

1.70 (1.44 - 1.99)

2.96 (2.46 - 3.53)

5.36 (0.65 - 19.36)

2.98 (2.48 - 3.55)

K00-K93

Digestive system

2.36 (2.20 - 2.53)

7.40 (6.60 - 8.27)

7.97 (6.91 - 9.14)

10.26 (3.33 - 23.92)

8.01 (6.96 - 9.17)

N00-N99

Genitourinary system

1.95 (1.74 - 2.17)

10.47 (8.96 - 12.16)

4.54 (3.14 - 6.34)

12.21 (0.31 - 68.02)

4.62 (3.22 - 6.42)

R00-R99

Other

0.92 (0.68 - 1.22)

3.48 (2.25 - 5.15)

7.43 (5.15 - 10.39)

21.58 (5.87 - 55.24)

7.99 (5.65 - 10.96)

V01-Y98

External

1.44 (1.34 - 1.54)

2.64 (2.34 - 2.98)

8.58 (7.96 - 9.22)

15.25 (11.72 - 19.51)

8.88 (8.28 - 9.52)

  1. Data sources: BCCDC Public Health Microbiology and Reference Laboratory, BC Ministry of Health Services, and BC Vital Statistics Agency.
  2. SNR=single non-reactive; MNR=multiple non-reactive; REAC=reactive at first test; SERO=seroconverter; SMR=standardized mortality ratio.