Evaluation of a community intervention program in Japan using Framingham risk score and estimated 10-year coronary heart disease risk as outcome variables: a non-randomized controlled trial

Table 4 Comparison of changes in cardiovascular disease risk between intervention and control groups at 18-month follow-up

		N	Baseline	18-month	Intervention vs. Control
			Mean ± S.D.	Mean ± S.D.	Difference	P-value^a
Weight, kg	Intervention	238	65.4 ± 7.9	63.8 ± 8.2	-1.08	0.003
Weight, kg	Control	1040	66.0 ± 8.7	65.4 ± 9.2	-1.08	0.003
BMI, kg/m²	Intervention	238	25.7 ± 2.2	25.1 ± 2.3	-0.38	0.007
BMI, kg/m²	Control	1040	25.7 ± 2.3	25.5 ± 2.6	-0.38	0.007
Waist, cm	Intervention	238	90.8 ± 5.7	88.9 ± 6.5	-1.13	0.039
Waist, cm	Control	1040	90.6 ± 5.9	90.0 ± 6.7	-1.13	0.039
SBP, mmHg	Intervention	238	133.9 ± 14.5	131.2 ± 14.0	-0.91	0.520
SBP, mmHg	Control	1040	135.2 ± 16.1	132.4 ± 14.8	-0.91	0.520
DBP, mmHg	Intervention	238	79.6 ± 9.6	78.1 ± 9.0	0.27	0.778
DBP, mmHg	Control	1040	80.7 ± 10.5	78.4 ± 9.9	0.27	0.778
HDL-C, mg/dl	Intervention	238	58.6 ± 15.0	58.6 ± 14.8	1.10	0.214
HDL-C, mg/dl	Control	1040	56.6 ± 15.1	56.3 ± 15.3	1.10	0.214
LDL-C, mg/dl	Intervention	238	134.2 ± 29.1	127.0 ± 27.9	0.59	0.823
LDL-C, mg/dl	Control	1040	133.9 ± 31.5	127.5 ± 31.7	0.59	0.823
TG, mg/dl	Intervention	238	143.6 ± 74.2	136.5 ± 76.2	-25.1	0.021
TG, mg/dl	Control	1040	163.4 ± 131.1	156.7 ± 119.4	-25.1	0.021
HbA_1c,%	Intervention	238	5.32 ± 0.39	5.31 ± 0.39	-0.03	0.429
HbA_1c,%	Control	1040	5.35 ± 0.66	5.38 ± 0.57	-0.03	0.429
Framingham risk score, score	Intervention	238	13.9 ± 2.4	14.0 ± 2.5	-0.39	0.022
Framingham risk score, score	Control	1040	13.9 ± 2.7	14.1 ± 2.9	-0.39	0.022
Mean 10-year CHD risk,%	Intervention	238	8.7 ± 5.8	8.8 ± 5.9	-0.85	0.027
	Control	1040	9.3 ± 6.4	9.8 ± 6.6

BMI = body mass index, waist = waist circumference, SBP = systolic blood pressure, DBP = diastolic blood pressure, HDL-C = high-density lipoprotein cholesterol, LDL-C = low-density lipoprotein cholesterol, TG = Triglycerides, HbA1c = Hemoglobin, CHD = coronary heart disease.
^aby covariance analysis adjusted for baseline values, age, sex and intervention times.

ISSN: 1471-2458