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Table 7 Causes associated with DRP (N = 191)

From: Drug-related problems in type 2 diabetes mellitus patients with dyslipidemia

Code

Detailed classification

n (%)

C1

Drug/Dose selection

277 (56.5)

C1.1

Inappropriate drug selection

36 (7.3)

C1.2

Inappropriate dosage selection

69 (14.1)

C1.4

Pharmacokinetic problems, incl. ageing/deterioration in organ function and interactions

84 (17.1)

C1.5

Synergistic/preventive drug required and not given

48 (9.8)

C1.6

Deterioration/improvement of disease state

11 (2.2)

C1.7

New symptom or indication revealed/presented

12 (2.4)

C1.8

Manifest side effect, no other cause

17 (3.6)

C2

Drug use process

22 (4.4)

C2.1

Inappropriate timing of administration and/or dosing intervals

6 (1.2)

C2.2

Drug underused/under-administered

5 (1.0)

C2.3

Drug overused/over-administered

3 (0.6)

C2.4

Therapeutic drug level not monitored

3 (0.6)

C2.5

Drug abused (unregulated overuse)

3 (0.6)

C2.6

Patient unable to use drug/form as directed

2 (0.4)

C3

Information

31 (6.4)

C3.1

Instructions for use/taking not known

17 (3.6)

C3.2

Patient unaware of reason for drug treatment

5 (1.0)

C3.4

Patient unable to understand local language

7 (1.4)

C3.5

Lack of communication between healthcare professionals

2 (0.4)

C4

Patient/Psychological

140 (28.5)

C4.1

Patient forgets to use/take drug

36 (7.3)

C4.2

Patient has concerns with drugs

11 (2.2)

C4.3

Patent suspects side-effect

3 (0.6)

C4.4

Patient unwilling to carry financial costs

8 (1.6)

C4.5

Patient unwilling to bother physician

14 (2.9)

C4.6

Patient unwilling to change drugs

1 (0.2)

C4.7

Patient unwilling to adapt life-style

45 (9.2)

C4.8

Burden of therapy

1 (0.2)

C4.9

Treatment not in line with health beliefs

19 (3.9)

C4.10

Patient takes food that interacts with drugs

2 (0.4)

C5

Logistics

18 (3.6)

C5.1

Prescribed drug not available (anymore)

8 (1.6)

C5.2

Prescribing error (only in case of slip of the pen)

8 (1.6)

C5.3

Dispensing error (wrong drug or dose dispensed)

2 (0.4)

C6

Others

3 (0.6)

C6.2

No obvious cause

3 (0.6)

Total

 

*491 (100.0)

  1. *A DRP associated with one or more causes. Causes of code C1.3 (More cost-effective drug available), C3.3 (Patient has difficulties reading/understanding Patient Information Form/Leaflet) and C6.1 (Other cause) were not listed in the table as none of the DRPs were associated with these causes.