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Table 4 Definition of causes associated with DRP

From: Drug-related problems in type 2 diabetes mellitus patients with dyslipidemia

Code

Primary domain

Code

Cause associated with DRP

C1

Drug/Dose selection

C1.1

Inappropriate drug selection

The cause of the DRP is related to the selection of the drug and/or dosage schedule

 

C1.2

Inappropriate dosage selection

C1.3

More cost effective drugs available

  

C1.4

Pharmacokinetic problems, incl. ageing/deterioration in organ function and interactions

  

C1.5

Synergistic/preventive drug required and not given

  

C1.6

Deterioration/improvement of disease state

  

C1.7

New symptom or indication revealed/presented

  

C1.8

Manifest side effect, no other cause

C2

Drug use process

C2.1

Inappropriate timing of administration and/or dosing intervals

The cause of the DRP can be related to the way the patient uses the drug, in spite of proper dosage instructions (on the label)

  

C2.2

Drug underused/under-administered

  

C2.3

Drug overused/over-administered

  

C2.4

Therapeutic drug level not monitored

  

C2.5

Drug abused (unregulated overuse)

  

C2.6

Patient unable to use drug/form as directed

C3

Information

C3.1

Instructions for use/taking not known

The cause of the DRP can be related to a lack or misinterpretation of information

 

C3.2

Patient unaware of reason for drug treatment

C3.3

Patients has difficulties reading patient information form/leaflet

  

C3.4

Patient unable to understand local language

  

C3.5

Lack of communication between healthcare professionals

C4

Patient/Psychological

C4.1

Patient forgets to use/take drug

The cause of the DRP can be related to the personality or behavior of the patient.

  

C4.2

Patient has concerns with drugs

  

C4.3

Patent suspects side-effect

  

C4.4

Patient unwilling to carry financial costs

  

C4.5

Patient unwilling to bother physician

  

C4.6

Patient unwilling to change drugs

  

C4.7

Patient unwilling to adapt life-style

  

C4.8

Burden of therapy

  

C4.9

Treatment not in line with health beliefs

  

C4.10

Patient takes food that interacts with drugs

C5

Logistics

C5.1

Prescribed drug not available (anymore)

The cause of the DRP can be related to the logistics of the prescribing or dispensing mechanism

  

C5.2

Prescribing error (only in case of slip of the pen)

  

C5.3

Dispensing error (wrong drug or dose dispensed)

  

C5.1

Prescribed drug not available (anymore)

C6

Others

C6.1

Other cause, specify

C6.2

No obvious cause

Total

   
  1. Adapted from: [5, 22].