A prospective population-based cohort study of lactation and cardiovascular disease mortality: the HUNT study

BMC Public Health

Table 3 Hazard ratios and 95% CIs for all causes and cardiovascular disease mortality in nulliparous and parous women by two categories of lifetime lactation duration, stratified by age (n = 21,889)

	No. of persons	Person-years	All causes					Cardiovascular disease
			No. of deaths	Mortality rate^a	Simple model^b	Fully adjusted model^c		No. of deaths	Mortality rate^a	Simple model^b	Fully adjusted model^c
					HR	HR	95% CI			HR	HR	95% CI
Women <65 years
*Total*	16,672	237,286	670	28				115	5
Ever lactated	14,968	213,175	587	28	1.00	1.00	Referent	98	5	1.00	1.00	Referent
Never lactated	532	7,491	33	44	1.44	1.33	0.93, 1.89	11	15	2.85	2.86	1.51, 5.39
Nulliparous	1,172	16,620	50	30	1.16	0.96	0.69, 1.33	6	4	0.82	0.41	0.16, 1.04
Women ≥65 years
*Total*	5,217	60,685	2,460	405				1,131	186
Ever lactated	4,382	51,588	1,987	385	1.00	1.00	Referent	914	177	1.00	1.00	Referent
Never lactated	125	1,480	53	358	1.05	1.01	0.77, 1.33	26	176	1.14	1.11	0.77, 1.69
Nulliparous	710	7,617	420	551	1.24	1.20	1.06, 1.36	191	251	1.21	1.20	1.00, 1.44

Abbreviations: HUNT2 The second Nord-Trøndelag Health Survey, HR hazard ratio, CI confidence interval.
^aIncidence per 10,000 person-years.
^bAdjusted for maternal age.
^cAdjusted for age, smoking status, physical activity, education, marital status and parity.
The HUNT2 Survey, 1995-2010.

ISSN: 1471-2458