Interaction between alcohol drinking and obesity in relation to colorectal cancer risk: a case-control study in Newfoundland and Labrador, Canada

Zhao, Jinhui; Zhu, Yun; Wang, Peizhong Peter; West, Roy; Buehler, Sharon; Sun, Zhuoyu; Squires, Josh; Roebothan, Barbara; McLaughlin, John R; Campbell, Peter T; Parfrey, Patrick S

doi:10.1186/1471-2458-12-94

Table 2 The demographic characteristics of CRC cases and controls and the prevalence rates of alcohol consumption by subgroup among cases and controls in the NL population-based case-control study of CRC in 1999-2003

From: Interaction between alcohol drinking and obesity in relation to colorectal cancer risk: a case-control study in Newfoundland and Labrador, Canada

Demographics	Case		Control		Case Drinkers^b		Control Drinkers
	N	%^a	N	%^a	N	% (95% CI)	N	% (95% CI)
Age group
20-54	186	26.5	185	25.8	126	67.7 (± 6.7)	131	70.8 (± 6.5)
55-64	242	34.5	264	36.8	154	63.6 (± 6.0)	174	65.9 (± 5.7)
65-74	274	39.0	268	37.4	152	55.5 (± 5.9)	148	55.2 (± 5.9)
Sex
Female	276	39.3	293	40.9	97	35.1 (± 5.6)	114	38.9 (± 5.6)
Male	426	60.7	424	59.1	335	78.6 (± 3.9)	339	80.0 (± 3.9)
Region		*
Urban	302	43.0	353	49.2	196	64.9 (± 5.4)	237	67.1 (± 4.9)
Rural	400	57.0	364	50.8	236	59.0 (± 4.8)	216	59.3 (± 5.0)
Education		***
High school or less	446	63.53	349	48.68	251	56.2 (± 4.5)	201	57.6 (± 5.2)
College+	256	36.47	368	51.32	181	70.7 (± 5.6)	252	68.5 (± 4.8)
Marital status
Married	540	76.92	579	80.75	364	64.9 (± 4.9)	382	65.9 (± 3.8)
Single/div./sep./wid.	162	23.08	138	19.25	86	53.1 (± 7.7)	71	51.4 (± 8.3)
Family history of CRC		***
No	540	76.92	614	85.63	342	63.3 (± 4.1)	394	64.1 (± 3.8)
Yes	162	23.08	103	14.37	90	55.5 (± 7.7)	59	57.2 (± 9.5)
Diabetes		***
No	555	79.06	623	86.89	97	35.1 (± 5.6)	114	38.9 (± 5.6)
Yes	147	20.94	94	13.11	335	78.6 (± 3.9)	339	80.0 (± 3.9)
Any laxatives use		***
No	573	81.62	657	91.63	97	35.1 (± 5.6)	114	38.9 (± 5.6)
Yes	129	18.38	60	8.37	335	78.6 (± 3.9)	339	80.0 (± 3.9)
Obesity		*
No (BMI < 30)	503	71.7	556	77.5	295	58.6 (± 4.3)	359	64.6 (± 4.0)
Yes (BMI ≥ 30)	199	28.4	161	22.5	137	68.6 (± 6.2)	94	58.4 (± 7.6)
Cigarette smoking		***
No	201	28.6	170	37.7	70	34.9 (± 6.7)	127	47.0 (± 5.9)
Yes	501	71.4	447	62.3	362	72.3 (± 4.0)	326	72.9 (± 4.1)
Cholesterol level		**
Low	494	70.4	451	62.9	303	61.3 (± 4.3)	286	63.4 (± 4.4)
High	208	29.6	266	37.1	129	62.0 (± 6.6)	167	62.8 (± 5.8)
Aspirin		*
No	522	74.4	492	68.6	306	58.6 (± 4.2)	306	62.2 (± 4.3)
Yes	180	25.6	225	31.4	126	70.0 (± 6.7)	147	65.3 (± 6.2)
Fruits daily		***
≤ 2 servings	519	73.9	471	65.7	312	60.1 (± 4.2)	295	62.6 (± 4.3)
3+ servings	183	26.1	246	34.3	120	65.6 (± 6.9)	158	64.0 (± 7.8)
Calcium pills/tablets		***
No	608	86.6	568	79.2	386	63.5 (± 4.8)	383	67.4 (± 3.8)
Yes	94	13.4	149	21.8	46	48.9 (± 10.1)	70	47.0 (± 8.0)
Total	702	100.0	717	100.0	432	61.5 (± 3.6)	453	63.2 (± 3.6)

^aColumn% and X ²: *P < 0.05 **P < 0.01 ***P < 0.001
^bNumber, percentage of drinkers and 95% CI of the percentage

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