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Table 5 Pooled estimates effect of pre-pregnancy care

From: Pre-pregnancy care for women with pre-gestational diabetes mellitus: a systematic review and meta-analysis

Dichotomous outcomes of pre-pregnancy care

No of studies [reference]

Risk Ratio [95% Confidence interval]

Congenital malformation

13 [7, 8, 14, 17–19, 21, 23, 24, 26, 30, 31, 33]

0.25 [0.16-0.37]

PM

6 [7, 8, 14, 18, 21, 31]

0.34 [0.15-0.75]

Maternal hypoglycemia

2 [7, 26]

1.51 [1.15,1.99]

Continuous outcomes

Number of studies references

Means difference (95% CI)

The difference in the level of glycosylated Hemoglobin A1c

5 [7, 19, 24, 26, 33]

−2.43 [−2.27 to −2.58]