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Table 2 Preoperative radiotherapy (RT) (followed by planned surgical admission) in 5,437 incident rectal cancer patients

From: Hospital factors and patient characteristics in the treatment of colorectal cancer: a population based study

  Total (N=5437) Preoperative RT (N=727) Random-effect model*
  No. % OR 95% CI P
Age (years)      
 ≤60 1,082 19.2 1   <0.001
 61-70 1,707 14.8 0.71 (0.57-0.90)  
 71-80 1,958 11.4 0.51 (0.40-0.65)  
 >80 690 6.1 0.24 (0.16-0.35)  
Gender      
 Male 3,375 14.2 1   0.03
 Female 2,062 12.1 0.77 (0.64-0.93)  
Educational level      
 Secondary or more 813 13.9 1   <0.001
 Intermediate 1,244 15.3 1.35 (1.03-1.77)  
 Primary 2,869 11.7 1.41 (1.09-1.83)  
 Unknown 511 17.4 1.16 (0.79-1.71)  
Marital status      
 Married 3,720 13.3 1   <0.001
 Unmarried 1,352 11.5 0.99 (0.80-1.23)  
 Unknown 365 20.8 0.84 (0.58-1.20)  
Disease staging      
 Absence of metastases 4,836 13.9 1   0.01
 Presence of metastases 601 8.8 0.47 (0.35-0.65)  
Comorbidity (Charlson index)      
 0 4,068 14.1 1   0.01
 ≥1 1,369 11.2 0.73 (0.59-0.90)  
Year of admission      
 2000 654 6.9 1   <0.001
 2001 706 9.6 1.51 (1.00-2.29)  
 2002 617 12.3 1.96 (1.30-2.95)  
 2003 607 15.3 2.76 (1.85-4.11)  
 2004 729 16.0 2.98 (2.02-4.40)  
 2005 691 16.5 2.90 (1.96-4.29)  
 2006 738 15.2 2.82 (1.90-4.17)  
 2007 695 14.7 3.04 (2.03-4.56)  
RT service      
 Absent 2,775 9.4 1   <0.001
 Present 2,662 17.5 2.24 (1.77-2.85)  
Distance to RT service (min.)      
 Same city or <15’ 2,576 15.6 1   <0.001
 15’ to <30’ 1,984 12.2 0.97 (0.80-1.18)  
 ≥30’ 877 9.6 0.82 (0.60-1.12)  
Hospital volume (annual caseload)      
 >25 3,076 17.6 - * <0.001
 11-25 1,778 6.8 - *  
 ≤10 583 11.1 - *  
  1. *Given the correlation between hospital volume and presence of RT service, these predictors were not included in the models simultaneously.
  2. Unmarried includes single, separated, divorced and widowed.
  3. OR: odds ratio, CI: confidence interval, APR-DRG: all-patient-refined-diagnosis-related group, RT: radiotherapy.