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Table 4 Lifetime costs, health gain and cost-effectiveness of cardiovascular disease prevention in Australia

From: Improving the cost-effectiveness of cardiovascular disease prevention in Australia: a modelling study

 

Lifetime health gain (QALYs)

Lifetime intervention costs to Government ($billion)

Lifetime intervention costs to Patients ($billion)

Lifetime treatment costs averted ($billion)

Cost-effectiveness* ($/QALY)

Current practice

270,000 (220,000 to 310,000)

$12 ($12 to $12)

$2.6 ($2.6 to $2.6)

-$3.4 (−$4.4 to -$2.4)

$41,000 ($34,000 to $52,000)

Existing single risk factor-based guidelines

180,000 (120,000 to 240,000)

$7.4 ($5.1 to $9.9)

$3.5 ($2.4 to $4.7)

-$2.3 (−$3.4 to -$1.3)

$49,000 ($40,000 to $60,000)

Absolute risk (≥15%)

67,000 (44,000 to 91,000)

$1.3 ($0.9 to $1.8)

$0.8 ($0.5 to $1.0)

-$0.7 (−$1.0 to -$0.4)

$21,000 ($17,000 to $26,000)

Absolute risk (≥10%)

150,000 (97,000 to 200,000)

$3.5 ($2.4 to $4.6)

$1.9 ($1.3 to $2.6)

-$1.5 (−$2.3 to -$0.9)

$27,000 ($22,000 to $32,000)

Absolute risk (≥5%)

– including statins <10%

330,000 (220,000 to 450,000)

$10.0 ($7.0 to $14.0)

$5.5 ($3.8 to $7.4)

-$3.7 (−$5.7 to -$2.2)

$37,000 ($31,000 to $44,000)

– excluding statins <10%

290,000 (190,000 to 390,000)

$6.5 ($4.5 to $8.6)

$4.3 ($2.9 to $5.7)

-$3.2 (−$4.8 to -$1.9)

$27,000 ($21,000 to $33,000)

Absolute risk (≥5%) assuming the cheaper price of statins in New Zealand

– including statins <10%

330,000 (220,000 to 450,000)

$5.1 ($3.5 to $6.8)

$3.7 ($2.6 to $5.0)

-$3.7 (−$5.7 to -$2.2)

$16,000 ($12,000 to $20,000)

– excluding statins <10%

290,000 (190,000 to 390,000)

$4.7 ($3.3 to $6.3)

$3.6 ($2.5 to $4.8)

-$3.2 (−$4.8 to -$1.9)

$18,000 ($14,000 to $24,000)

  1. NB. All values are rounded to two significant figures. Health gains and costs are presented as mean and 95% uncertainty interval, and cost-effectiveness ratio as median and 95% uncertainty interval. Costs are presented in 2008 Australian dollars. QALY – quality-adjusted life year*. A value of $50,000/QALY is often considered a threshold for cost-effectiveness in Australia.