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Table 2 Symptoms according to VDGF exposure

From: Association between occupational exposure and the clinical characteristics of COPD

 

All n = 591

VDGF + N = 209

VDGF – 382

P value

Chronic bronchitis (%)

73.3

75.3

72.2

NS (a)

Shortness of breath (MRC)

2 [1–2]

2 [1–2]

2 [1–2]

NS (b)

Life-time wheeze (%)

65

71.9

61.1

0.0371 (a)

Exacerbations/patient/yr

1 [0–3]

1 [0–3]

1 [0–3]

NS (b)

FEV1 (postBD, % predicted)

49 [35–66]

51.6 [37.2–67.1]

47.2 [33.7–65.3]

0.08 (b)

GOLD stages (%)

   

0.15 (a)

I

5.6

7.7

4.5

 

II

43

44.5

42.2

 

III

33.2

33.5

33

 

IV

18.3

14.4

20.4

 

Current sputum1

2 [1–4]

3 [1 – 4].

2 [1 – 4].

0.035 (b)

Current wheeze1*

1 [0–2]

2 [0 – 3].

1 [0 – 2].

0.002 (b)

Work related respiratory disability *

1 [0–1]

1 [0 – 2].

0 [0 – 1].

0.001 (b)

SGRQ total score *

43.7 [30.3-60.0]

46.2 [32.5-63.4]

42.0 [29.9-58.2]

NS (b)

  1. 1: during the previous year (answers to SGRQ questions, symptoms domain).
  2. *: analysis restricted to patients with available SGRQ: n = 424 (VDGF+: n = 144; VDGF-: n = 280). Answers were converted to continuous variables. Data are median [Q1 – Q3] or %.
  3. (a) = Chi-Square Test.
  4. (b) = Wilcoxon rank-sum test.
  5. p values are for differences between VGDF + and VGDF.