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Table 3 Adjusted HRs and PARs of metabolic disorders for all-cause and CVD-related mortality in women stratified by menopausal status (N = 1143)

From: Age- and gender-specific population attributable risks of metabolic disorders on all-cause and cardiovascular mortality in Taiwan

All-cause mortality
Peri-menopausal Post-menopausal
45 ≤ Age < 55 Age ≥ 55
  Death (%)(n = 15) Adj HR†
(95% CI) ‡
PAR (%)
(95% CI)‡
Death
(%)(n = 63)
Adj HR†
(95% CI) ‡
PAR (%)
(95% CI)‡
MetS 4 (26.7) 1.70 (0.33-4.86) 13.4 (1.6-35.3) 35 (55.6) 1.89 (1.05-3.59)* 19.5 (4.1-32.9)
High WC 8 (53.3) 2.33 (0.66-10.90) 26.5 (3.2-51.6) 46 (73.0) 1.48 (0.79-3.44) 16.6 (1.5-39.4)
AH 6 (40.0) 2.48 (0.64-9.38) 25.0 (3.0-47.1) 42 (66.7) 2.14 (1.21-4.27)* 33.2 (11.6-50.6)
DM 0 (0.0) N/A§ N/A§ 22 (34.9) 1.99 (1.02-3.64)* 11.8 (2.18-20.0)
High TG 3 (20.0) 1.64 (0-4.70) 9.1 (0.7-26.7) 17 (27.0) 1.20 (0.64-2.31) 3.2 (0.3-13.5)
Low HDL-C 2 (13.3) 0.61 (0-2.21) N/A§ 21 (33.3) 1.12 (0.58-1.97) 2.9 (0.4-16.2)
CVD-related mortality
Peri-menopausal Post-menopausal
45 ≤ Age < 55 Age ≥ 55
  Death (%)
(n = 3)
Adj HR†
(95% CI) ‡
PAR (%)
(95% CI)‡
Death (%)
(n = 28)
Adj HR†
(95% CI) ‡
PAR (%)
(95% CI)‡
MetS 2 (66.7) 6.21 (N/A§) 41.9 (4.3-86.8) 18 (64.3) 2.95 (1.39-8.71)* 42.5 (19.4-64.7)
High WC 3 (100) N/A§ N/A§ 22 (78.6) 3.38 (1.52-15.1)* 47.8 (21.2-71.3)
AH 2 (66.7) 6.44 (N/A§) 52.8 (4.0-100) 18 (64.3) 1.93 (0.88-5.50) 36.0 (6.37-68.1)
DM 0 N/A§ N/A§ 11 (39.3) 2.78 (1.16-7.31)* 22.8 (4.99-38.6)
High TG 2 (66.7) 11.5 (N/A§) 45.6 (11.2-85.7) 9 (32.1) 1.65 (0.51-4.88) 11.4 (1.4-30.4)
Low HDL-C 1 (33.3) 3.96 (N/A§) 28.0 (2.99-75.0) 15 (53.6) 2.51 (1.06-6.11)* 24.5 (5.22-42.3)
  1. †: CAD, stroke, BMI, alcohol drinking, smoking, betel nut chewing, exercise, and income were adjusted for in the model.
  2. ‡: The 95% CI obtained by taking the 2.5 and 97.5 percentiles of the recalculated PARs among one thousand bootstrapped datasets.
  3. §: N/A: not available. The adjusted HR was less than 1 due to small number of observations, yielding a negative corresponding PAR.
  4. #: CVD-related mortality (ICD-9th revision codes 250, 390-398, and 401-441).
  5. BMI, body mass index; CAD, coronary artery disease; CI, confidence interval; CVD, cardiovascular disease; DM, diabetes mellitus; AH, arterial hypertension; HDL-C, high-density lipoprotein cholesterol; HR, hazard ratio; MetS, metabolic syndrome; PAR, population attributable risk; TG, triglycerides; WC, waist circumference