Table 1 Eligibility

Inclusion criteria:

1

Diagnosed diabetes mellitus type 2

2

Age 18–75 years

3

BMI ≥ 27 kg/m²

Exclusion criteria:

6

Pregnancy or lactation during the study

7

Inadequate expression of the Dutch language (spoken and written)

8

Inability to lose ≥ 5% of bodyweight during the first 8 weeks of VLCD

9

Severe psychiatric problems

10

Significant cardiac arrhythmias, unstable angina, decompensated congestive heart failure, major organ system failure, untreated hypothyroidism and/or myocardial infarction, end-stage renal disease, cerebrovascular accident or major surgery in the last 3 months.