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Table 2 Quality assessment of studies of calcium supplementation during pregnancy to prevent stillbirths from maternal hypertensive disorders:

From: Impact of interventions to prevent and manage preeclampsia and eclampsia on stillbirths

Quality Assessment

Directness

Summary of findings

No. of studies (Ref)

Design

Limitations

Consistency

Generalizability to Population of Interest

Generalizability to intervention of Interest

Events in intervention group

Events in control group

Relative Risk ( 95 % CI)

Stillbirth: Moderate outcome specific quality

3

RCT

None

Consistent (I2 =0)

Yes all from developing countries

Dose of calcium supplementation ranged from 1.5-2 g/day in all the included studies

117

145

0.81 (0.63-1.03)a

Perinatal mortality: Low outcome specific quality

4

RCTs

None

Consistent (I2 =0)

Yes All from developing countries

Dose of calcium supplementation ranged from 1.5-2 g/day in all the included studies

154

179

0.86 (0.70-1.07)a