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Table 2 Quality assessment of studies of calcium supplementation during pregnancy to prevent stillbirths from maternal hypertensive disorders:

From: Impact of interventions to prevent and manage preeclampsia and eclampsia on stillbirths

Quality Assessment Directness Summary of findings
No. of studies (Ref) Design Limitations Consistency Generalizability to Population of Interest Generalizability to intervention of Interest Events in intervention group Events in control group Relative Risk ( 95 % CI)
Stillbirth: Moderate outcome specific quality
3 RCT None Consistent (I2 =0) Yes all from developing countries Dose of calcium supplementation ranged from 1.5-2 g/day in all the included studies 117 145 0.81 (0.63-1.03)a
Perinatal mortality: Low outcome specific quality
4 RCTs None Consistent (I2 =0) Yes All from developing countries Dose of calcium supplementation ranged from 1.5-2 g/day in all the included studies 154 179 0.86 (0.70-1.07)a