Table 2 Application of standardized rules for choice of final outcome to estimate effect of zinc supplementation on mortality due to diarrhea, pneumonia and malaria in children less than 5 years of age

Cause specific mortality (diarrhea)

4

18% reduction;

RR = 0.82 (0.64, 1.05)

(Low quality of evidence)

Incidence of diarrhea

14

13% reduction;

RR = 0.87 (0.81, 0.94)

Rule 6 is applied

(Moderate quality of evidence)

(Effect Recommended for LiST)

Cause specific mortality (pneumonia)

(Zinc only studies)

4

15% reduction;

RR = 0.85 (0.65, 1.11)

Rule 6 applied

(Low quality of evidence)

(Effect Recommended for LiST)

Pneumonia morbidity

6

19% reduction;

RR = 0.81 (0.73, 0.90)

Rule 6 applied

(Moderate quality of evidence)