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Table 6 Application of standardized rules for choice of final outcome to estimate effect of breastfeeding on the reduction of diarrhea mortality

From: Breastfeeding and the risk for diarrhea morbidity and mortality

Outcome Measures Application of Standard Rules
0-5 months*   
Diarrhea Incidence n=3; 1594 events
The risk of incident diarrhea is 1.26 (0.81-1.95) for predominant BF; 1.68 (1.03-2.76) for partial BF; 2.65 (1.72-4.07) for not BF as compared to EBF
Rule 2: APPLY
Diarrhea Mortality n=2; 80 events
The risk of diarrhea mortality is 2.28 (0.85-6.13) for predominant BF; 4.62 (1.81-11.76) for partial BF; 10.52 (2.79-39.6) for not BF as compared to EBF
 
6-11 months   
Diarrhea Incidence n=2; 646 events
The risk of incident diarrhea is 1.32 (1.06-1.63) for not BF as compared to any BF
Rule 2: APPLY
Diarrhea Mortality n=2; 84 events
The risk of diarrhea mortality is 1.47 (0.67-3.25) for not BF as compared to any BF
 
12-23 months   
Diarrhea Incidence n=0; use estimate for 6-11 mos: n=2; 646 events
The risk of incident diarrhea is 1.32 (1.06-1.63) for not BF as compared to any BF
Rule 2: APPLY
Diarrhea Mortality n=2; 84 events
The risk of diarrhea mortality is 2.57 (1.10-6.01) for not BF as compared to any BF
 
  1. *Evaluating events for studies where reference category is EBF