Figure 5

Expected value of perfect information. (A) Expected value of perfect population information for a model using the input parameters of general population aged 18 years, and using characteristics of vaccine hypothesis as follows: 31.2% of vaccine efficacy, 210 THB vaccine costs, 80% acceptance rate, 10-year protection, and 3 boosters with full courses. THB: Thai baht as of 2009 value. (B) Partial expected value of perfect information of parameters used in the model at a ceiling ratio of 100,000 THB per QALY gained for the provision of a HIV vaccination program for the general population aged 18 years and using characteristics of vaccine hypothesis as follows: 31.2% vaccine efficacy, 210 THB vaccine costs, 80% acceptance rate, 10-year protection, and 3 boosters with full courses. THB: Thai baht as of 2009 value; QALY: quality adjusted life year; pHIVneg_HIVpos_Base: the probability of HIV infection among the general population; pAsym_Sym: the probability of transition from HIV infection with asymptomatic state to a symptomatic state; pAsym_Death: the probability of transition from HIV infection with asymptomatic state to death; pSym_AIDS: the probability of transition from HIV infection with symptomatic state to AIDS state; HzFnSymp_death: the probability of death from HIV infection with symptomatic state analyzed from parametric survival analysis; HzFnAIDS_death: the probability of death during AIDS state analyzed from parametric survival analysis; HzFnReg1_Reg2: the probability of switching ART first regimens to second regimens among AIDS patients analyzed from parametric survival analysis; HzFnReg2_Reg3: the probability of switching ART second regimens to third regimens among AIDS patients analyzed from parametric survival analysis; C_ComEn: individual cost of community engagement; C_Screen: HIV screening cost; C_PreCou: cost of pre-counseling; TC_Asymp: total treatment cost of HIV infection in asymptomatic state; TC_Sym; total treatment cost of HIV infection in symptomatic state; TC_NewAIDS: total treatment cost of new AIDS patient; TC_AIDS_Reg1: total cost of treatment with the first ART regimens of AIDS patient; TC_AIDS_Reg2: total cost of treatment with the second ART regimens of AIDS patient; TC_AIDS_Reg3: total cost of treatment with the third ART regimens of AIDS patient; TC_AIDS: total cost of other treatment of AIDS patient; Uasym: utility weight of HIV infection with asymptomatic patient; Usym: utility weight of HIV infection with symptomatic patient; UAIDS utility weight of AIDS patient; Risk: percentage of change in the risk behavior post-vaccination; Boost: the duration of vaccine protection; and Vac_eff: vaccine efficacy