| NOD2 mutation negative | NOD2 mutation heterozygous | NOD2 mutation homozygous |
---|---|---|---|
Frequency of NOD2 genotype in CD probands | 65% | 27% | 8% |
Frequency of NOD2 genotype among FDRs | 75% | 22% | 3% |
Frequency of NOD2 genotype in controls | 87% | 12% | 1% |
Risk to FDRs of developing CD conferred by genotype | 2% | 4% | 15% |