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Table 5 Multivariable logistic regression analyses assessing associations with low birthweight (n = 3650)

From: Stressful life events, social health issues and low birthweight in an Australian population-based birth cohort: challenges and opportunities in antenatal care

 

< 2500 grams

No. (%)

Unadjusted OR

(95% CI)

Model 1

Adj OR

(95% CI)

Model 2

Adj OR

(95% CI)s

Model 3

Adj OR

(95% CI)

Model 4

Adj OR

(95% CI)

Stressful life events/social health issues

      

No issues

40 (3.3)

1.00 ref

1.00 ref

1.00 ref

1.00 ref

1.00 ref

1-2 issues

75 (4.1)

1.27 (0.9-1.9)

1.26 (0.9-1.9)

1.24 (0.8-1.8)

1.22 (0.8-1.8)

1.13 (0.8-1.7)

≥3 issues

38 (6.2)

1.94 (1.2-3.1)

1.80 (1.1-2.9)

1.77 (1.1-2.8)

1.72 (1.1-2.8)

1.44 (1.0-2.3)

Smoking status

      

Non-smoker

120 (4.0)

1.00 ref

1.00 ref

1.00 ref

1.00 ref

1.00 ref

Quit in pregnancy

9 (3.0)

0.76 (0.4-1.5)

0.72 (0.36-1.4)

0.69 (0.3-1.4)

0.71 (0.4-1.4)

0.67 (0.3-1.3)

Smoking throughout pregnancy

24 (7.5)

1.97 (1.3-3.1)

1.76 (1.1-2.8)

1.75 (1.1-2.8)

1.57 (1.0-2.6)

1.82 (1.1-3.0)

Maternal country of birth

      

Australia

113 (3.8)

1.00 ref

 

1.00 ref

1.00 ref

1.00 ref

Overseas - English speaking

13 (5.8)

1.58 (0.9-2.8)

 

1.66 (0.9-3.0)

1.54 (0.8-2.8)

1.60 (0.9-2.9)

Overseas - Non-English speaking

27 (6.4)

1.76 (1.1-2.7)

 

1.85 (1.2-2.9)

1.80 (1.1-2.8)

1.90 (1.2-3.0)

Maternal pre-pregnant BMI

      

Underweight (< 18.5)

11 (6.8)

1.62 (0.8-3.1)

 

1.37 (0.7-2.6)

1.37 (0.7-2.6)

1.39 (0.7-2.7)

Normal weight (18.5-24.9)

93 (4.3)

1.00 ref

 

1.00 ref

1.00 ref

1.00 ref

Overweight (25-29.9)

33 (4.0)

0.92 (0.6-1.4)

 

0.92 (0.6-1.4)

0.94 (0.6-1.4)

0.81 (0.5-1.2)

Obese (≥30)

16 (3.1)

0.69 (0.4-1.2)

 

0.69 (0.4-1.2)

0.72 (0.4-1.2)

0.54 (0.3-0.9)

Educational attainment

      

Completed year 12

113 (3.9)

1.00 ref

 

1.00 ref

1.00 ref

1.0 ref

Did not complete year 12

40 (5.4)

1.46 (1.0-2.1)

 

1.36 (0.9-2.0)

1.30 (0.9-1.9)

1.27 (0.9-1.9)

Number of antenatal visits

      

≥5 visits

133 (3.8)

1.00 ref

  

1.00 ref

 

< 5 visits

20 (14.3)

4.23 (2.6-7.0)

  

3.48 (2.1-5.8)

 

Risk of complications in pregnancy

      

Lower risk

40 (1.8)

1.00 ref

   

1.00 ref

Higher risk

113 (7.9)

4.72 (3.3-6.8)

   

4.83 (3.3-7.0)

  1. Model 1: exposures of main interest adjusted for smoking status
  2. Model 2: exposure of main interest adjusted for smoking status, maternal country of birth, maternal BMI, maternal education.
  3. Model 3: exposure of main interest adjusted for smoking status, maternal country of birth, maternal BMI, maternal education and number of antenatal visits
  4. Model 4: exposure of main interest adjusted for smoking status, maternal country of birth, maternal BMI, maternal education and risk of complications in pregnancy