Mixed linear models adjusted for age, demonstrating associations of educational attainment with longitudinal trajectories of mean systolic blood pressure (SBP) in (A) females and (B) males. Age adjustment refers to adjustment for baseline age and time from baseline age. Modeling for baseline age and time from baseline was as follows: age+age2+time+time2+ age*time+age*time2+age2*time. Error bars represent 95% confidence intervals. Framingham Offspring Study, 1971-2001.