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Table 5 Summary of hierarchical regression models in women: serum lipids on birth weight in model 1, adding life course exposures (cumulative socioeconomic disadvantage (SES) and cumulative adversity) in model 2, and current health behavior (smoking, snuff use, high alcohol consumption; estimates not shown) in model 3.

From: Fetal and life course origins of serum lipids in mid-adulthood: results from a prospective cohort study

Criterion

     Predictor

Model 1 = birth weight

 

Model 2 = + life course exposures

 

Model 3 = + current health behavior

 

ΔR2 (p)

b (SE)

β(p)

 

ΔR2 (p)

b (SE)

β(p)

 

ΔR2 (p)

b (SE)

β(p))

Final R2 (p)

HDL-C

.003 (.296)

   

.029 (.006)

   

.032 (.005)

  

.061 (< .001)

   Birthweight

 

0.04 (0.04)

.05 (.296)

  

0.02 (0.04)

.03 (.544)

  

0.02 (0.04)

.03 (.504)

 

   SES

     

-0.03 (0.02)

-.09 (.092)

  

-0.02 (0.02)

-.08 (.129)

 

   Adversity

     

-0.01 (0.01)

-.11 (.049)

  

-0.01 (0.01)

-.10 (.068)

 

TG

.019 (.006)

   

.023 (.010)

   

.010 (.241)

  

.053 (.002)

   Birthweight

 

-0.14 (0.05)

-.14 (.006)

  

-0.12 (0.05)

-.12 (.019)

  

-0.12 (0.05)

-.12 (.016)

 

   SES

     

0.02 (0.02)

.05 (.395)

  

0.01 (0.02)

.03 (.555)

 

   Adversity

     

0.02 (0.01)

.13 (.015)

  

0.02 (0.01)

.11 (.047)

 

Apo A1

.000 (.883)

   

.012 (.100)

   

.033 (.005)

  

.045 (.007)

   Birthweight

 

-3.62 (24.6)

-.01 (.883)

  

-10.9 (24.8)

-.02 (.660)

  

-10.4 (24.5)

-.02 (.671)

 

   SES

     

-5.44 (10.5)

-.03 (.604)

  

-4.58 (10.5)

-.02 (.662)

 

   Adversity

     

-7.04 (3.97)

-.010 (.077)

  

-7.20 (4.01)

-.10 (.074)

 

Apo B

.006 (.122)

   

.020 (.020)

   

.022 (.033)

  

.048 (.004)

   Birthweight

 

-32.3 (20.9)

-.08 (.122)

  

-24.3 (20.9)

-.06 (.246)

  

-26.5 (20.8)

-.06 (.203)

 

   SES

     

6.46 (8.83)

.04 (.465)

  

3.03 (8.86)

.02 (.733)

 

   Adversity

     

7.64 (3.35)

.12 (.023)

  

5.88(3.39)

.01 (.084)