Patient characteristic | Year of assessment | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | Total | Extended Mantel-Haenszel test for trend | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 |  | Number | % | Number | % | Number | % | Number | % | Number | % | Number | % | Number | % | chi-sq. | DF | p |
Number | Â | 247 | Â | 174 | Â | 213 | Â | 290 | Â | 213 | Â | 129 | Â | 1266 | Â | Â | Â | Â |
Sex | male | 102 | 41.3 | 75 | 43.1 | 94 | 44.1 | 105 | 36.2 | 81 | 38.0 | 51 | 39.5 | 508 | 40.1 | 1.41 | 1 | 0.24 |
 | female | 145 | 58.7 | 99 | 56.9 | 119 | 55.9 | 185 | 63.8 | 132 | 62.0 | 78 | 60.5 | 758 | 59.9 |  |  |  |
Chronic fever, cough or diarrhoea | no | 222 | 89.9 | 145 | 83.3 | 189 | 88.7 | 272 | 93.8 | 204 | 95.8 | 123 | 95.3 | 1155 | 91.2 | 15.2 | 1 | < 0.001 |
 | yes | 25 | 10.1 | 29 | 16.7 | 24 | 11.3 | 18 | 6.2 | 9 | 4.2 | 6 | 4.7 | 111 | 8.8 |  |  |  |
Bed-bound | not bedbound | 85 | 34.4 | 55 | 31.6 | 54 | 25.4 | 104 | 35.9 | 106 | 49.8 | 54 | 41.9 | 458 | 36.2 | 28.7 | 1 | < 0.001 |
 | bedridden less than half the day | 29 | 11.7 | 17 | 9.8 | 66 | 31.0 | 70 | 24.1 | 43 | 20.2 | 30 | 23.3 | 255 | 20.1 |  |  |  |
 | bedridden more than half the day | 133 | 53.8 | 102 | 58.6 | 93 | 43.7 | 116 | 40.0 | 64 | 30.0 | 45 | 34.9 | 553 | 43.7 |  |  |  |
Can leave house | yes | 173 | 71.2 | 128 | 75 | 130 | 61.0 | 203 | 72.2 | 151 | 72.9 | 81 | 68.1 | 866 | 70.2 | 0.77 | 1 | 0.38 |
 | no | 70 | 28.8 | 43 | 25 | 82 | 38.5 | 78 | 27.8 | 56 | 27.1 | 38 | 31.9 | 367 | 29.8 |  |  |  |
Needs help bathing | yes | 39 | 15.8 | 55 | 31.6 | 49 | 23.0 | 35 | 12.1 | 27 | 12.7 | 19 | 14.8 | 224 | 18.5 | 58.3 | 1 | < 0.001 |
 | no | 158 | 64.0 | 118 | 67.8 | 163 | 76.5 | 255 | 87.9 | 185 | 87.3 | 109 | 85.2 | 988 | 81.5 |  |  |  |
Needs help dressing | yes | 42 | 17.0 | 30 | 17.2 | 20 | 9.4 | 26 | 9.0 | 17 | 8.0 | 10 | 7.8 | 145 | 11.5 | 4.41 | 1 | 0.04 |
 | no | 205 | 83.0 | 144 | 82.8 | 193 | 90.6 | 262 | 90.3 | 196 | 92.0 | 119 | 92.2 | 1119 | 88.4 |  |  |  |
Needs help eating | yes | 22 | 8.9 | 19 | 10.9 | 4 | 1.9 | 12 | 4.2 | 11 | 5.2 | 6 | 4.7 | 74 | 5.9 | 7.27 | 1 | 0.01 |
 | no | 224 | 90.7 | 155 | 89.1 | 209 | 98.1 | 273 | 95.8 | 201 | 94.8 | 123 | 95.3 | 1185 | 94.1 |  |  |  |
Needs help walking | yes | 88 | 35.6 | 50 | 28.7 | 25 | 11.7 | 40 | 13.9 | 31 | 14.6 | 20 | 15.5 | 254 | 20.1 | 43 | 1 | < 0.001 |
 | no | 159 | 64.4 | 124 | 71.3 | 187 | 87.8 | 247 | 86.1 | 181 | 85.4 | 109 | 84.5 | 1007 | 79.9 |  |  |  |
Needs help with toileting | yes | 70 | 28.3 | 40 | 23.0 | 24 | 11.3 | 40 | 14.1 | 29 | 13.9 | 19 | 15.0 | 222 | 17.8 | 21.4 | 1 | < 0.001 |
 | no | 176 | 71.3 | 133 | 76.4 | 188 | 88.3 | 243 | 85.9 | 179 | 86.1 | 108 | 85.0 | 1027 | 82.2 |  |  |  |
Past TB | yes | 82 | 34.0 | 60 | 35.3 | 86 | 42.0 | 99 | 34.7 | 56 | 27.2 | 40 | 31.0 | 423 | 34.2 | 1.99 | 1 | 0.16 |
 | no | 159 | 66.0 | 110 | 64.7 | 119 | 58.0 | 186 | 65.3 | 150 | 72.8 | 89 | 69.0 | 813 | 65.8 |  |  |  |
On TB treatment at assessment | yes - pulmonary | 75 | 30.4 | 58 | 33.3 | 73 | 34.3 | 63 | 21.7 | 36 | 17.0 | 24 | 18.6 | 329 | 26.0 | 13.28 | 1 | < 0.001 |
 | yes - extra-pulmonary | 2 | 0.8 | 15 | 8.6 | 12 | 5.6 | 10 | 3.4 | 7 | 3.3 | 10 | 7.8 | 56 | 4.4 |  |  |  |
 | no | 170 | 68.8 | 101 | 58.0 | 128 | 60.1 | 217 | 74.8 | 169 | 79.7 | 95 | 73.6 | 880 | 69.5 |  |  |  |
HIV test done before assessment | yes | 47 | 19.0 | 72 | 41.4 | 97 | 45.5 | 186 | 64.1 | 154 | 72.3 | 96 | 74.4 | 652 | 51.5 | 185 | 1 | < 0.001 |
 | no | 200 | 81.0 | 102 | 58.6 | 116 | 54.5 | 104 | 35.9 | 59 | 27.7 | 33 | 25.6 | 614 | 48.5 |  |  |  |
ART status | on ART before initial assessment | 0 | 0.0 | 0 | 0 | 0 | 0.0 | 35 | 12.1 | 75 | 35.2 | 48 | 37.2 | 158 | 12.5 | 207 | 1 | < 0.001 |
 | on ART after initial assessment | 19 | 7.7 | 28 | 16.1 | 37 | 17.4 | 66 | 22.8 | 28 | 13.1 | 14 | 10.9 | 192 | 15.2 |  |  |  |
 | not on ART | 228 | 92.3 | 146 | 83.9 | 176 | 82.6 | 189 | 65.2 | 110 | 51.6 | 67 | 51.9 | 916 | 72.4 |  |  |  |
WHO staging | 2 | 30 | 12.1 | 17 | 9.8 | 15 | 7.0 | 21 | 7.2 | 30 | 14.2 | 18 | 14.0 | 131 | 10.3 | 2.84 | 1 | 0.092 |
 | 3 | 82 | 33.2 | 49 | 28.2 | 89 | 41.8 | 114 | 39.3 | 80 | 37.7 | 45 | 34.9 | 459 | 36.3 |  |  |  |
 | 4 | 135 | 54.7 | 108 | 62.1 | 109 | 51.2 | 155 | 53.4 | 102 | 48.1 | 66 | 51.2 | 675 | 53.3 |  |  |  |
Sputum sent for AFB | yes | 0 | 0 | 0 | 0 | 18 | 8.5 | 26 | 9.2 | 14 | 6.6 | 6 | 4.7 | 64 | 5.1 | 15.7 | 1 | < 0.001 |
 | no | 247 | 100 | 174 | 100 | 195 | 91.5 | 263 | 92.9 | 199 | 93.4 | 122 | 95.3 | 1200 | 94.9 |  |  |  |
Referred for ART | yes | 0 | 0 | 0 | 0 | 12 | 5.6 | 39 | 13.5 | 36 | 16.9 | 23 | 17.8 | 110 | 8.7 | 76.8 | 1 | < 0.001 |
 | no | 247 | 100 | 174 | 100 | 201 | 94.4 | 250 | 86.5 | 177 | 83.1 | 106 | 82.2 | 1155 | 91.2 |  |  |  |
Died, alive or lost to follow up | died | 171 | 69.2 | 126 | 72.4 | 131 | 61.5 | 129 | 44.5 | 68 | 31.9 | 27 | 20.9 | 652 | 51.5 | 153 | 1 | < 0.001 |
 | lost | 8 | 3.2 | 9 | 5.2 | 29 | 13.6 | 27 | 9.3 | 19 | 8.9 | 3 | 2.3 | 95 | 7.5 |  |  |  |
 | only seen once | 23 | 9.3 | 4 | 2.3 | 6 | 2.8 | 13 | 4.5 | 8 | 3.8 | 22 | 17.1 | 76 | 6.0 |  |  |  |
 | alive | 45 | 18.2 | 35 | 20.1 | 47 | 22.1 | 121 | 41.7 | 118 | 55.4 | 77 | 59.7 | 443 | 35.0 |  |  |  |
 |  | Rate |  | Rate |  | Rate |  | Rate |  | Rate |  | Rate |  | Rate |  |  |  |  |
First visit rate per 1000 population | 4.2 | Â | 2.5 | Â | 2.7 | Â | 3.5 | Â | 2.5 | Â | 2.2 | Â | 2.9 | Â | 31.2 | 1 | < 0.001 | |
Follow up visit rate per 1000 pop | 10.7 | Â | 18.1 | Â | 23.6 | Â | 27.0 | Â | 21.4 | Â | 17.6 | Â | 20.1 | Â | 84.2 | 1 | < 0.001 | |
 |  | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Pearson r | Anova p | |
Body mass index | 18.6 | 3.2 | 17.9 | 2.3 | 18.1 | 2.7 | 18.3 | 3.2 | 18.3 | 2.9 | 18.0 | 3.3 | 18.3 | 3.0 | -0.022 | 0.47 | ||
Age | Â | 31.8 | 7.9 | 33.0 | 8.0 | 32.8 | 8.1 | 34.8 | 9.0 | 34.4 | 8.1 | 34.0 | 9.2 | 33.5 | 8.4 | 0.11 | < 0.001 |