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Table 5 Frequency, age-adjusted risk and risk ratio of the occurrence of lung cancer, identified by death records, between baseline and 31 December 2005 by number of categories of adverse childhood experiences (ACEs) and smoking status among 16,901 adults

From: Erratum to: Adverse childhood experiences are associated with the risk of lung cancer: a prospective cohort study

   

Relative risk of lung cancer*

 

N |

Person-

Time (yrs)

Deaths |

Mortality

Rate**

Model A

RR (95% CI)

Model B

RR (95% CI)

Categories of ACEs, No.

      

   0

6124 |

44,592

44 |

26.0

1.00 (referent)

1.00 (referent)

   1

4411 |

31,709

22 |

19.3

0.80 (0.48-1.34)

0.74 (0.44, 1.23)

   2

2681 |

19,045

22 |

66.4

1.48 (0.89-2.49)

1.30 (0.77, 2.18)

   3

1599 |

11,056

11 |

51.3

1.52 (0.78-2.96)

1.17 (0.59, 2.29)

   4 or 5

1637 |

11,259

8 |

30.0

1.32 (0.61-2.83)

1.00 (0.46, 2.16)

   6, 7, or 8

449 |

2901

4 |

62.7

3.55 (1.25-10.09)

2.34 (0.81, 6.75)

     

P for trend = 0.025

P for trend = 0.251

Smoking status

      

   Never

8589 |

61,713

11 |

8.5

 

1.00 (referent)

   Former

6879 |

49,379

73 |

58.0

 

5.92 (3.10-11.30)

   Current,<20 cig/d

870 |

5748

10 |

129.7

 

12.43 (5.23-29.57)

   Current, >20 cig/d

563 |

3722

17 |

357.1

 

28.15 (12.77-62.08)

Total

16,901 |

120,562

111 |

31.1

  
  1. ACEs, adverse childhood experiences RR, risk ratio CI, confidence interval
  2. * Underlying cause of death from lung cancer defined by ICD-9 code 162 for deaths between 1995-1998; ICD-10 code C34 for deaths between 1999 and 2005.
  3. ** Rate (per 100,000 person-years) age-standardized to the 2000 Census population for California.
  4. Model A adjusted for age, sex, race/ethnicity, education, married, financial problems
  5. Model B adjusted for age, sex, race/ethnicity, education, married, financial problems, smoking status, parental smoking history. In addition to the RR estimates for ACE score, we show the RR estimates for smoking status from the regression model.