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Factor analysis of self-treatment in diabetes mellitus: a cross-sectional study

  • Negin Masoudi Alavi1Email author,
  • Leila Alami1,
  • Sedigheh Taefi1 and
  • Gholamali Shojae Gharabagh1
Contributed equally
BMC Public Health201111:761

DOI: 10.1186/1471-2458-11-761

Received: 15 November 2010

Accepted: 4 October 2011

Published: 4 October 2011

Abstract

Background

Self-treatment is a treatment of oneself without professional help, which may cause health-related consequences. This investigation examined the self-treatment behaviors in patients with diabetes mellitus in Iran/kashan.

Methods

The patients who referred to the clinic of diabetes and those who were admitted to the General hospital in the city of Kashan due to diabetes mellitus were asked to participate in this cross-sectional study. For data collection, The 25 item questionnaire of Likert scale type with four scales was used. Factor analysis was performed to define the patterns of self-treatment.

Results

398 patients participated in the study. The mean age of the study population was 54.9 ± 12.9 years. The majority (97%) had type 2 diabetes. 50% of patients reported self- treatment. The self-treatment score was 45.8 ± 8.8 (25-100). Female gender, lower education and co-morbid illnesses of hypertension, hyperlipidemia and cardiac disease had significant relationship with self-treatment. The factor analysis procedure revealed seven factors that explained the 43% of variation in the self-treatment. These seven factors were categorized as knowledge, deficiencies of formal treatments, available self-treatment methods, physician related factors, the tendency to use herbal remedies, underlying factors such as gender and factors related to diabetes.

Conclusions

There is a medium tendency for self-treatment in diabetic patients. The assessment of self-treatment practices must be an essential part of patients' management in diabetes care.

Keywords

Diabetes Mellitus Self-Treatment Factor analysis

Background

Self treatment is a treatment of oneself without professional help, to alleviate an illness or a condition [1]. Persons with a strong self-treatment tendency might not seek any formal treatment [2]. Self-treatment is often associated with adverse effects, related to the improper use of substances [3]. Self-treatment is a common behavior all over the world. It is estimated that 83.3% of patients commit self-treatment in Iran [4]. In a study, the 75% of participants were reported to take analgesics for pain management, which were successful only in 45% of cases [5]. The symptom iceberg means that the majority of symptoms were self-treated. It is estimated that only one symptom in 37 led to a consultation [6].

Diabetes mellitus contributes to the increased morbidity and mortality [7]. Considering the burden of the disease, self-treatment might have severe consequences [8]. In a case report, a diabetic patient tried to treat the foot injury by using a hot paraffin footbath, but severe burn injury developed and after surgical debridement and a long healing period of six months, the patient recovered [9]. Self-treatment in diabetes is generally considered to be safe. Using herbal remedies or bush medicines for treating the symptoms of diabetes is common [8]. Even in some cases such as symptomatic hypoglycemia, self-treatment might be life-saving [10].

Self-treatment is a multidimensional construct involving complex processes, which influence personal and public health. Income, ethnicity, educational level, age, cultural forces and health perspectives are among the factors that might influence this behavior [3]. At present, little is known about the self-treatment behaviors in diabetes mellitus [11]. The aim of the current study was to assess the prevalence of self-treatment behaviors in diabetes mellitus in Kashan and to determine the variables and patterns that could influence this behavior. The cross-sectional research method and factor analysis were used for this study.

Methods

In this cross-sectional study, all the patients who referred to the clinic of diabetes in Kashan and those who were hospitalized in General hospital of the city due to diabetes mellitus during January to June 2009 were asked to participate in the study. The inclusion criteria for this study were as follows: age above 18 years old and diagnosed with diabetes mellitus by Glucose Tolerance Test for at least six months. 398 of the total 420 patients accepted to take part in the study. The difference between the patients who accepted and those who refused to participate in this study were not remarkable. The research was approved by the ethical committee of Kashan University of Medical Sciences, and the informed consent was obtained from each subject.

The items of the questionnaire were extracted from the interviews in a qualitative research. The self-treatment experiences that were quoted by patients were changed to the items of the questionnaire. The details of this research have been described elsewhere [12]. Item analysis of the questionnaire was carried out in a pilot study. 40 patients completed the questionnaire in the pilot study. The Cronbach Coefficient Alpha of the questionnaire was calculated in the pilot study. Considering the findings, 10 items with low internal consistency were dropped. The final questionnaire contained 25 items with a 4-point Likert scale ranging from always to never. Every item represented a self-treatment behavior or the possible factors that could influence it, such as "I use herbal remedies or bush medicines for treating diabetes " or "I believe the herbs are harmless." The internal consistency reliability of the questionnaire was 0.85. The content validity of the questionnaire was confirmed by the experts in the diabetes field. The patients could obtain a score between 25 and 100 from the questionnaire. The higher scores indicated the greater self-treatment tendency. The raw score was used for data analysis.

The variable including age, sex, type of diabetes, modes of treatment, education, duration of diabetes and co-morbid illnesses were also recorded. The patients completed the questionnaire in the presence of an interviewer, who intervened if there were any difficulties in reading and understanding the questions.

The data was compiled and statistically analyzed using the 16.0 release of SPSS program for Windows. The relationships between variables and self-treatment scores were analyzed by Kruskal-Wallis and Mann-Whitney test. Analysis of covariance used to adjust for possible confounders. To explore the self-treatment behaviors and its related variables, exploratory factor analysis was conducted using the maximum likelihood technique with varimax rotation. The items and variables were assigned to the composite scale on which it had the highest factor loading. The Kaiser-Mayer-Olkin (KMO) measure and Bartlett's test of sphericity were conducted to find sampling adequacy. The goals of exploratory factor analysis were to determine the number of fundamental influences underlying a domain of variables, to quantify the extent to which each variable was associated with the factors.

Results

Sample characteristics

398 of 420 patients participated in the study. The mean age of the study population was 54.9 ± 12.9 years. The patients had 9.5 ± 8.3 years, history of diabetes. The majority (97%) had type 2 diabetes and 273 (68.5%) were female. The 47.7% of patients had hypertension and 27.6% had hyperlipidemia. The 32.4 percent of patients were treated by insulin injections while 67.6% of patients received oral drugs. The socio-demographic characteristics of subjects and their relationship with self-treatments are presented in Table 1.
Table 1

The characteristics of the patients and its relationship with self-treatment

  

N

%

Self-

treatment

Score

Mean

Rank

P value

Covariant

       

Age

Education

Gender

Female

273

68.5

46.8 ± 8.6

214.5

0.0001*

F = 3.38

F = 0.974

 

Male

125

31.5

43.7 ± 8.9

170.4

 

p = 0.066

p = 0.324

Treatment

Insulin

129

32.4

46.7 ± 8.4

208.16

0.2

  
 

Oral pills

269

67.6

45.4 ± 8.9

192.43

   

Kind of referring

Inpatient

198

49.7

46.5 ± 8.7

210.03

0.099

  
 

Outpatient

200

50.3

45.1 ± 8.9

190.97

   

Education

Illiterate

174

43.7

47.1 ± 8.4

217.53

0.014*

F = 0.172

 
 

Under diploma

176

44.3

44.9 ± 9.2

183.55

 

p = 0.678

 
 

Diploma & higher

48

12

44.7 ± 8.6

183.7

   

Renal problems Θ

Yes

82

20.8

45.4 ± 9.3

194.22

0.578

  
 

No

316

79.2

45.9 ± 8.7

202.15

   

Hyperlipidemia ¥

Yes

110

27.6

47.4 ± 8.8

220.18

0.035*

F = 1.48

F = 3.15

 

No

288

72.4

45.2 ± 8.7

192.94

 

p = 0.224

p = 0.076

Cardiac disease ¶

Yes

133

33.4

47 ± 8.6

217.25

0.04*

F = 1.06

F = 3.09

 

No

265

66.6

45.2 ± 8.9

192.06

 

p = 0.3

p = 0.08

Hypertension δ

Yes

190

47.7

47.1 ± 9.1

216.9

0.007*

F = 0.57

F = 2.5

 

No

208

52.3

44.6 ± 8.5

185.52

 

p = 0.45

p = 0.116

*Significant relationship

Θ Glumerular Filtration Rate less than 60 mL/min/1.73m2

¥ Cholestrol more than 200 mg/dL

¶ The symptoms of angina pectoris according to physician diagnosis

δ Sistolic blood pressure above 140 mmHg or diastolic pressure above 90 mmHg

Self-treatment behaviors

23% of patients chose always or most of the time for practicing self-treatment. 27% chose sometimes and 50% selected never for self-treatment practice. The self-treatment score was 45.8 ± 8.8 (Minimum 25, Max 75, Median = 45, Mode = 39). Female gender, lower education and co-morbid illnesses of hypertension, cardiac disease and hyperlipidemia showed significant relationship with self-treatment. The self-treatment score in patients who referred to the outpatient clinics and those who were hospitalized was not significantly different. Using analysis of covariance to adjust for age and education did not modify the results (Table 1).

Self-medication was a common form of self-treatment (27%). Using herbs, plants and opium were other forms of self-treatment (12.2%). The patients tended to use self-treatment for symptoms such as fatigue and pain and to reduce the blood-glucose level. Most patients seek formal treatments (54.3%) after their unsuccessful self-treatment and when they face severe problems following chronic and acute complications of diabetes such as hypoglycemia or renal problems.

Factor analysis

This study showed the KMO of 0.618 and the Bartlett's test of sphericity of 0.000 (less than 0.05), making the sample of this study adequate for factor analysis. From scree plot levels off to a linear decreasing pattern, seven major factors were elicited (Figure 1).
https://static-content.springer.com/image/art%3A10.1186%2F1471-2458-11-761/MediaObjects/12889_2010_Article_3565_Fig1_HTML.jpg
Figure 1

Scree Plot of eigenvalues of self-treatment variables

These seven factors were named: Knowledge, deficiencies of formal treatments, available self-treatment methods, physician related factors, tendency to use herbal remedies, underlying factors such as gender, and factors related to diabetes. The accumulated variance reached 43% (Table 2).
Table 2

Summary of factors' structures

Factors

Factors'

Name

Variables

Loading

Eigenvalue

Percent of

variance

Accumulated

Variance (%)

Factor 1

Knowledge

General Education

0.433

3.46

10%

10%

  

Age

0.932

   
  

Diabetes related education

0.422

   

Factor 2

Deficiencies of formal treatments

Fears of treatments

0.327

2.75

8%

18%

  

Long stay for visiting a physician

0.405

   
  

Costly treatments

0.520

   
  

Frustration of treatment

0.611

   

Factor 3

Available self-treatment methods

Home remedies

0.922

1.81

6%

24%

  

Doing nothing and waiting to see the progress

0.587

   
  

Self-medication

0.371

   
  

Use of herbals

0.352

   

Factor 4

Physician related factors

Easy physician consultation

0.358

1.64

5%

29%

  

Believing physician's competencies

0.452

   
  

Respect of physician

0.355

   
  

Tendency to changing physician

0.437

   
  

Having several physicians

0.464

   

Factor 5

Tendency to use herbal remedies

Believing effectiveness of herbals

0.507

1.59

5%

34%

  

Believing Herbals are safe

0.403

   

Factor 6

Underlying factors

Female Gender

0.634

1.48

5%

39%

  

Family support

0.378

   
  

Co-morbid illnesses

0.376

   

Factor 7

Factors related to diabetes

Type of Diabetes

0.402

1.32

4%

43%

  

Duration of diabetes

0.384

   
  

Treatment modality (Insulin, oral pills)

0.576

   

Discussion

In this study, there was a medium tendency for self-treatment among diabetic patients.

Female gender, lower education and co-morbid illnesses of hypertension, cardiac disease and hyperlipidemia showed the relationship with self-treatment. If the treatment with Insulin or renal complications were considered as the indicator of severity of the diabetes, it seems that severity of the diabetes is not significantly related to self-treatment, but the symptoms that patient experience might determine his or her self-treatment behavior. Patients prefer to seek formal treatments in severe symptoms. The inpatient and outpatient situations were not related to self-treatment behaviors. This might represent the fact that self-treatment is a basic health-related behavior that is not affected by temporary situations.

Different factors could influence self-treatment behaviors. Giovannini found that self-treatment is the most common first therapeutic choice in the patients [13]. However, we should consider that self-treatment is a broad concept, and a process which can be divided into three-stages of self-diagnosis, self-treatment and self-monitoring [14]. The patients' treatment behaviors can be ranged from seeking care from doctors as outpatients, waiting to see the progress of symptoms, resting or consulting books, using home remedies to self-treatments [15].

In our study, patients showed different self-treatment behaviors. Self-medication is the most prevalent self-treatment behavior. 27% of patients reported self medication. In Tabriz 81.64% of individuals embarked on self-treatment using chemical drugs [16]. This is much higher compared to our study. It seems that self-treatment is more common in general population than in patients with diabetes mellitus.

The next aim of this study was to identify the background factors of self-treatment in diabetes. The seven factors were extracted from the data. In a study, the most common factors' underlying self-drug consumption was negligence of the disease (30%) and inability to afford the visit fees of the physicians (14.7%) [4]. In a different study in Iran, it was found that costly treatments (32.4%) and lack of time (23.7%) were the reasons why patients refused to visit the physicians [17]. Another study showed that symptomatic therapy by physician, insignificance of diseases from the patients' viewpoints, and cost of the treatments were the main reasons for practicing self-medication [18]. The comparable factors can be seen in our study. Like us, Jirojwong also found that compared to men, women tend more to use home remedies and show more self-treatment behaviors [15]. The women had significantly lower education compared to men, which can explain the difference. But studies show that there are basic differences between men and women in treatment-seeking behaviors and self-treatment [15, 12, 19, 5].

It is possible that the medium tendency of self-treatment in patients to be related to their tendency of not choosing the extreme options in the questionnaire. Convenience sampling was used for this research, and it should be noted that the participants of this study were patients with diabetes seeking care at the ambulatory clinic or admitted to the hospital due to diabetes complications, which might be a potential source of bias and limits the generalization of the findings.

Conclusion

People make decisions about their methods of treatment based on their experiences, which is formed as a response to particular illness episodes and interactions of many overlapping components. The explosion of information on medicine has enhanced the pluralistic system and patients can choose different self-treatment methods [20].

We need more information about self-treatment behaviors to distinguish its negative and potential positive impacts on the treatment process and to develop better educational programs. Education in diabetes mellitus must be very precise. Patients need to know when they should consult a physician immediately and when they can take action by themselves. We need to know the common self-treatment modalities in our community and predict their hazards and benefits. The assessment of self-treatment practices must be an essential part of patients' management in diabetes care.

Notes

Declarations

Acknowledgements

This study was supported by a grant from Kashan University of Medical sciences.

Authors’ Affiliations

(1)
Faculty of Nursing, Kashan University of Medical Sciences

References

  1. The American Heritage: Stedman's Medical Dictionary. 2004, Baltimore: William & Wilkins. Press, 2Google Scholar
  2. Wetzels R, Van Eijken M, Grol R, Wensing M, Van Weel C: Self management is not related to lower demand for primary care in independent living elderly. J Am Geriatr Soc. 2005, 53: 918-919. 10.1111/j.1532-5415.2005.53278_8.x.View ArticlePubMedGoogle Scholar
  3. Riley-Doucet CK, Fouladbakhsh JM, Vallerand AH: Canadian and American self-treatment of pain: a comparison study. Rural Remote Health. 2004, 4: 286-287.PubMedGoogle Scholar
  4. Asefzadeh S, Anbarloei M, Habibi SH, Rezaei M: Self medication among the in patients of Qazvin teaching hospitals. J of Qazvin Univ of Med Sc. 2002, 20: 48-54.Google Scholar
  5. Vallerand AH, Fouladbakhsh J, Templin T: Patients' choices for the self-treatment of pain. Appl Nurs Res. 2005, 18: 90-96. 10.1016/j.apnr.2004.07.003.View ArticlePubMedGoogle Scholar
  6. Stevenson FA, Britten N, Barry CA, Bradley CP, Barber N: Self-treatment and its discussion in medical consultations: How is medical pluralism managed in practice?. Soc Sci Med. 2003, 57: 513-527. 10.1016/S0277-9536(02)00377-5.View ArticlePubMedGoogle Scholar
  7. Whittemore R, Melkus D'Eramo, Grey M: Metabolic control, self-management and psychosocial adjustment in women with type 2 diabetes. J Clin Nurs. 2005, 14: 195-203. 10.1111/j.1365-2702.2004.00937.x.View ArticlePubMedGoogle Scholar
  8. Moss MC, McDowell JR: Rural Vincentians' (Caribbean) beliefs about the usage of non-prescribable medicines for treating Type 2 diabetes. Diabet Med. 2005, 22: 1492-1496. 10.1111/j.1464-5491.2005.01676.x.View ArticlePubMedGoogle Scholar
  9. Putz Z, Nadas J, Jermendy G: Severe but preventable foot burn injury in diabetic patients with peripheral neuropathy. Med Sci Monit. 2008, 14: CS89-91.PubMedGoogle Scholar
  10. Sommerfield AJ, Ewing FME, Strachan MWJ, Deary IJ, Aitken G, Frier BM: Self-treatment of mild symptomatic hypoglycaemia by people with insulin-treated diabetes. Diabet Med. 2003, 20: 686-690. 10.1046/j.1464-5491.2003.09281.x.View ArticlePubMedGoogle Scholar
  11. Mcdonald IG, Daly J: On patient judgement. Intern Med J. 2001, 31: 184-187. 10.1046/j.1445-5994.2001.00036.x.View ArticlePubMedGoogle Scholar
  12. Masoudi Alavi N, Izadi F, Ebadi A, Hajbagheri A: Self Treatment Experience in Diabetes Mellitus Type 2. Iranian J Endocrinol Metab. 2009, 6: 581-588.Google Scholar
  13. Giovannini P, Heinrich M: Xki yoma' (our medicine) and xki tienda (patent medicine)-- Interface between traditional and modern medicine among the Mazatecs of Oaxaca, Mexico. J Ethnopharmacol. 2009, 121: 383-399. 10.1016/j.jep.2008.11.003.View ArticlePubMedGoogle Scholar
  14. Charlton BG: Self-management of psychiatric symptoms using over-the-counter (OTC) psychopharmacology: The S-DTM therapeutic model - Self-diagnosis, self-treatment, self monitoring. Med Hypotheses. 2005, 65: 823-828. 10.1016/j.mehy.2005.07.013.View ArticlePubMedGoogle Scholar
  15. Jirojwong S, MacLennan R: Manegament episodes of incapacity by families in rural and remote queensland. Aust J Rural Health. 2002, 10: 249-255. 10.1046/j.1440-1584.2002.00424.x.View ArticlePubMedGoogle Scholar
  16. Somi MH, Behshid M, Zamanzadeh V, Abbasalizadeh Sh, Jabbari H, Yavarikia P, Pezeshkian M: Health seeking behavior of residents in northwestern Tabriz. Med J Tabriz. 2003, 59: 81-77.Google Scholar
  17. Heidari MR, Karami Nejad M, Rezaei Far M, Rezaei Dastjerdi E: Determination of the most prevalent reasons for requesting drugs without prescription in Kerman pharmacies. J Babol U Med Sc. 2000, 4: 32-37.Google Scholar
  18. Tavakoli R: The survey of important socio-economic & cultural variables influencing self medication. Daneshvar. 2002, 34: 9-12.Google Scholar
  19. Amariles P, Gonzlez LI, Giraldo NA: Prevalence of self-treatment with complementary products and therapies for weight Loss: A randomized, cross-sectional study in overweight and obese patients in Colombia. Curr Therap Res. 2006, 67: 66-78. 10.1016/j.curtheres.2006.02.001.View ArticleGoogle Scholar
  20. Chui WK, Li SC: Advice-giving on self-medication: perspectives of community pharmacists and consumers in Singapore. J Clin Pharm Ther. 2005, 30: 225-231. 10.1111/j.1365-2710.2005.00637.x.View ArticlePubMedGoogle Scholar
  21. Pre-publication history

    1. The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-2458/11/761/prepub

Copyright

© Alavi et al; licensee BioMed Central Ltd. 2011

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.