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Table 1 Baseline characteristics of this study according to the body weight changes

From: Risk of fracture according to temporal changes of low body weight changes in adults over 40 years: a nationwide population-based cohort study

Variables

Body weight changes from 2007 to 2009

p-value

N to N

N to La

L to N

L to L

Participants (n)

1,666,364

13,141

12,677

21,043

 

Age (years)

55.19 ± 9.7

57.65 ± 11.93

55.09 ± 11.38

56.08 ± 11.78

 < .001

Age (n)

    

 < .001

  < 65

1,365,976(81.97)

9,286(70.66)

9,920(78.25)

15,728(74.74)

 

  ≥ 65

300,388(18.03)

3,855(29.34)

2,757(21.75)

5,315(25.26)

 

Sex (n)

    

 < .001

 Men

876,672(52.61)

5,726(43.57)

5,604(44.21)

9,861(46.86)

 

 Women

789,692(47.39)

7,415(56.43)

7,073(55.79)

11,182(53.14)

 

Height (cm)

162.18 ± 8.71

160.81 ± 8.45

160.98 ± 8.57

161.73 ± 8.3

 < .001

Weight (kg)

63.74 ± 10.29

46.39 ± 5.19

50.7 ± 6.32

45.64 ± 5.24

 < .001

Smoking (n)

    

 < .001

 Non

1,040,628(62.45)

8,818(67.1)

8,341(65.8)

13,458(63.95)

 

 Ex

311,799(18.71)

1,399(10.65)

1,634(12.89)

2,304(10.95)

 

 Current

313,937(18.84)

2,924(22.25)

2,702(21.31)

5,281(25.1)

 

Alcohol consumption(n)b

    

 < .001

 Non

953,558(57.22)

8,837(67.25)

8,231(64.93)

13,933(66.21)

 

 Mild to moderate

605,840(36.36)

3,675(27.97)

3,887(30.66)

6,176(29.35)

 

 Heavy

106,966(6.42)

629(4.79)

559(4.41)

934(4.44)

 

Regular exercise (n)c

374,781(22.49)

2,222(16.91)

2,031(16.02)

3,210(15.25)

 < .001

Low income (n)d

318,842(19.13)

2,744(20.88)

2,668(21.05)

4,274(20.31)

 < .001

Comorbidities

 DM (n)

202,779(12.17)

1,130(8.6)

761(6)

1,195(5.68)

 < .001

 Hypertension (n)

602,227(36.14)

3,145(23.93)

2,510(19.8)

3,725(17.7)

 < .001

 Dyslipidemia (n)

427,031(25.63)

1,746(13.29)

1,737(13.7)

2,251(10.7)

 < .001

 CKD (n)

100,980(6.06)

817(6.22)

617(4.87)

1,011(4.8)

 < .001

Laboratory findings

 BMI (kg/m2)

24.15 ± 2.84

17.89 ± 0.62

19.52 ± 1.5

17.4 ± 0.84

 < .001

 WC (cm)

81.53 ± 8.31

68.68 ± 6.13

71.06 ± 6.32

66.8 ± 5.51

 < .001

 Systolic BP (mmHg)

124 ± 14.87

118.37 ± 15.65

118.73 ± 15.36

116.81 ± 15.52

 < .001

 Diastolic BP (mmHg)

77.05 ± 9.9

73.68 ± 10.1

73.91 ± 9.92

73 ± 9.95

 < .001

 Fasting glucose

99.93 ± 23.83

96.37 ± 27.21

94.57 ± 20.41

94.19 ± 21.97

 < .001

 Total cholesterol (mg/dL)

198.01 ± 36.97

187.09 ± 34.34

191.86 ± 34.92

187.19 ± 33.63

 < .001

 HDL

54.53 ± 22.28

61.67 ± 19.33

60.47 ± 15.12

63.14 ± 17.55

 < .001

 LDL

117.69 ± 45.79

107.01 ± 39.1

112.03 ± 48.57

106.36 ± 38.34

 < .001

 eGFR (ml/min/1.73m2)

86.86 ± 34.16

89.76 ± 36.31

90.52 ± 31.44

91 ± 35.72

 < .001

 TG

115.58(115.49–115.68)

83.99(83.32–84.68)

90.33(89.57–91.1)

81.46(80.96–81.95)

 < .001

  1. Numeric parameters are expressed as mean ± standard deviation and categorical parameters are expressed as counts and percentages in parentheses
  2. DM Diabetes mellitus, CKD Chronic kidney disease, BMI Body mass index, WC Waist circumference, BP Blood pressure, HDL High-density lipoprotein, LDL Low-density lipoprotein, eGFR Estimated glomerular filtration rate, TG Triglyceride
  3. aLow body weight was defined as body mass index under 18.5 kg/m2
  4. bAlcohol consumption was divided into 3 categories; Non (no alcohol consumption), Mild (under 30 g/day consumption), and heavy (over 30 g/day consumption)
  5. cRegular exercise is defined as performing over 30 min moderate intensity exercise over 5 times per a week or over 20 min vigorous intensity exercise over 3 times per a week
  6. dLow income is defined as total household monthly income belongs to lower 20% group among Korean entire population