Table 1 Baseline characteristics of study population by sex
Characteristic | Women | Men | Overall | Standardized difference | p-value |
|---|---|---|---|---|---|
N = 27,535 |  N = 24,894 |  N = 52,429 | |||
Age in years, median (Q1, Q3) | 43 (29, 56) | 42 (29, 56) | 42 (29, 56) | 0.03 | < 0.001 |
Major cardiovascular disease (recent myocardial infarction* or lifetime history of heart failure) | 552 (2.0%) | 633 (2.5%) | 1,185 (2.3%) | 0.04 | < 0.001 |
Hypertension | 6,288 (22.8%) | 5,987 (24.0%) | 12,275 (23.4%) | 0.03 | 0.001 |
Diabetes | 3,679 (13.4%) | 3,657 (14.7%) | 7,336 (14.0%) | 0.04 | < 0.001 |
Recent cancer* | 563 (2.0%) | 403 (1.6%) | 966 (1.8%) | 0.03 | < 0.001 |
Chronic obstructive pulmonary disease (COPD) | 1,236 (4.5%) | 1,230 (4.9%) | 2,466 (4.7%) | 0.02 | 0.015 |
Stage 4/5 chronic kidney disease (CKD)†| 167 (0.6%) | 183 (0.7%) | 350 (0.7%) | 0.02 | <0.001 |
Undetermined CKD status | 8,070 (29.3%) | 9,635 (38.7%) | 17,705 (33.8%) | 0.2 | |
Chronic dialysis | 55 (0.2%) | 91 (0.4%) | 146 (0.3%) | 0.03 | < 0.001 |
Frailty‡ | 1,020 (3.7%) | 774 (3.1%) | 1,794 (3.4%) | 0.03 | < 0.001 |