Table 3 Results of the multiple linear regression models for DHDs

Antidepressants

Year

2018

Ref.

Ref.

2019

0.19

0.06–0.32

0.005

0.42

0.14–0.70

0.004

2020

0.40

0.27–0.53

< 0.005

0.89

0.61–1.17

< 0.001

2021

0.74

0.61–0.87

< 0.005

1.76

1.48–2.04

< 0.001

Age

0–14

Ref.

Ref.

15–29

0.85

0.67–1.02

< 0.001

1.40

1.03–1.77

< 0.001

30–44

4.64

2.95–6.33

< 0.001

8.47

8.10–8.84

< 0.001

45–59

11.31

11.14–11.48

< 0.001

22.73

22.36–23.01

< 0.001

60–74

10.04

9.87–10.21

< 0.001

29.65

29.28–30.02

< 0.001

75–89

6.24

6.07–6.41

< 0.001

23.12

22.75–23.49

< 0.001

90 and older

0.80

0.63–0.97

< 0.001

4.14

3.77–4.51

< 0.001

Anxiolytics

Year

2018

Ref.

Ref.

2019

−0.01

−0.13-0.11

0.88

−0.03

−0.23-0.16

0.77

2020

0.20

0.08–0.32

0.001

0.44

0.24–0.63

< 0.001

2021

0.44

0.32–0.56

< 0.001

0.88

0.68–1.08

< 0.001

Age

0–14

Ref.

Ref.

15–29

0.62

0.46–0.78

< 0.001

0.75

0.49–1.01

< 0.001

30–44

5.61

5.45–5.77

< 0.001

6.82

6.56–7.08

< 0.001

45–59

14.42

14.26–14.58

< 0.001

19.29

19.03–19.55

< 0.001

60–74

11.00

10.84–11.16

< 0.001

25.00

24.74–25.26

< 0.001

75–89

5.25

5.09–5.41

< 0.001

16.62

16.36–16.88

< 0.001

90 and older

0.61

0.45–0.78

< 0.001

2.98

2.72–3.24

< 0.001

Hypnotics and sedatives

Year

2018

Ref.

Ref.

2019

0.06

0.02–0.10

0.004

0.06

−0.01-0.13

0.10

2020

0.17

0.13–0.21

< 0.001

0.25

0.18–0.32

< 0.001

2021

0.28

0.24–0.32

< 0.001

0.44

0.37–0.51

< 0.001

Age

0–14

Ref.

0.06–0.18

Ref.

15–29

0.12

0.76–0.88

< 0.001

0.14

0.04–0.24

< 0.001

30–44

0.82

2.71–2.83

< 0.001

1.28

1.18–1.38

< 0.001

45–59

2.77

3.91–4.03

< 0.001

4.63

4.53–4.73

< 0.001

60–74

3.97

2.90–3.02

< 0.001

7.91

7.81–8.01

< 0.001

75–89

2.96

0.37–0.49

< 0.001

7.70

7.60–7.80

< 0.001

90 and older

0.43

0.06–0.32

< 0.001

1.62

1.52–1.72

< 0.001