|  | e-interventions | Personalised digital interventions | |||||
---|---|---|---|---|---|---|---|---|
Hazardous/ harmful use | AUD | Students and young adults | Military and veterans | Women, child-bearing age | Cancer survivors | |||
Risk of bias | Meta-analyses (AMSTAR) | Low | Very low | Very low | Very low | Very low | Moderate | Very low |
RCTs | High | High | Moderate | Moderate | Moderate | High | High | |
Inconsistency | Meta-analyses | Inconsistent | Inconsistent | Consistent | NA (single study) | NA (single study) | NA (single study) | Consistent |
Heterogeneity of RCTs | Moderate | Moderate | Moderate | Very high | NR | Very low | Moderate | |
Indirectness | Applicable | Applicable | Applicable | US | May include low risk | May include low risk | Applicable | |
Imprecision | Confidence interval | Wide | Wide | Small | Moderate | Small | Moderate | Small |
Sample size | Thousands | Thousands | Thousands | Thousands | Thousands | Hundreds | Thousands | |
Small study effect (number of studies) | Yes (3), No (1) | No (2) | Yes (2), No (1), NR (3) | NR | No (1) | NR | Yes (1), No (1), NR (1) | |
Other | NA | NA | NA | Long-term | NA | NA | NA | |
Overall | Very low | Very low | Very low | Very low | Very low | Very low | Very low |