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Table 3 Analysis of the interaction of GBD and cardiometabolic risk factors associated with CVD

From: Gallbladder disease is associated with the risk of cardiovascular disease among Uyghurs in Xinjiang: a prospective cohort study

Subgroup

CVD Events

Person-Years

Rated

HRa(95%CI)

HRb(95%CI)

HRc(95%CI)

GBD

Hypertension

     

-

-

414

35,591

116.32

1.00 (reference)

1.00 (ref.)

1.00 (ref.)

-

 + 

385

12,842

299.8

2.58 (2.25,2.97)

1.89 (1.64,2.18)

1.82 (1.58,2.11)

 + 

-

150

3093

484.97

4.17 (3.46,5.02)

2.76 (2.28,3,35)

2.65 (2.19,3.23)

 + 

 + 

251

1790

1402.23

11.80 (10.08,13.81)

6.02( 5.09,7.12)

5.58 (4.71,6.62)

GBD

T2DM

      

-

-

681

46,083

147.78

1.00 (reference)

1.00 (ref.)

1.00 (ref.)

-

 + 

118

2350

502.13

3.40(2.79,4.13)

2.28 (1.87,2.77)

2.12 (1.74,2.58)

 + 

-

337

4380

769.41

5.15(4.52,5.87)

3.39 (2.96,3.89)

3.21 (2.80,3.69)

 + 

 + 

64

503

1272.37

8.54(6.61,11.03)

3.94 (3.03,5.140

3.50 (2.68,4.56)

GBD

Dyslipidemia

     

-

-

474

34,761

136.36

1.00 (reference)

1.00 (ref.)

1.00 (ref.)

-

 + 

325

13,672

237.12

1.74 (1.51,2.00)

1.34 (1.16,1.55)

1.10 (0.94,1.28)

 + 

-

224

2993

748.41

5.43 (4.63,6.36)

3.31 (2.81,3.91)

3.00 (2.54,3.56)

 + 

 + 

177

1890

936.51

6.81 (5.73,8.10)

3.80 (3.18,4.54)

2.98 (2.46,3.60)

GBD

Overweight

     

-

-

193

20,661

93.41

1.00 (reference)

1.00 (ref.)

1.00 (ref.)

-

 + 

606

27,772

218.21

2.34 (1.99,2.75)

1.62 (1.37,1.90)

1.27 (1.24,1.73)

 + 

-

77

1305

590.04

6.26 (4.80,8.15)

3.45 (2.63,4.52)

3.41 (2.60,4.47)

 + 

 + 

324

3578

905.54

9.60 (8.03,11.48)

4.79 (3.98,5.77)

4.05 (3.35,4.89)

GBD

Abdominal obesity

     

-

-

184

20,599

89.32

1.00 (reference)

1.00 (ref.)

1.00 (ref.)

-

 + 

615

27,834

220.95

2.48 (2.10,2.92)

1.58 (1.34,1.87)

1.25 (1.04,1.50)

 + 

-

71

1224

580.07

6.41 (4.87,8.43)

4.41 (3.34,5.81)

4.28 (3.24,5.65)

 + 

 + 

330

3659

901.89

10.01 (8.36,12.00)

4.48 (3.69,5.43)

3.30 (2.68,4.06)

  1. Model a was unadjusted
  2. Model b was adjusted for age and sex
  3. Model c was further adjusted for exercise, hypertension, T2DM, overweight, and HDL levels
  4. d Rate per 10,000 person-years. (GBD gallbladder disease, T2DM type 2 diabetes mellitus, CVD cardiovascular disease, HDL high-density lipoprotein cholesterol)