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Table 2 Factors associations with COVID-19 vaccination status (n = 3446) and sub-group analyses among preconception, pregnant, and breastfeeding individuals

From: Worries, beliefs and factors influencing perinatal COVID-19 vaccination: a cross-sectional survey of preconception, pregnant and lactating individuals

A. Total (n = 3446)

Vaccinated

OR (95% CI)

aOR (95% CI)

Variables

Yes = 1460

No = 1986

  
 

n (%)

n (%)

  

Spoken to HCP about vaccine during perinatal period

1149 (78.7)

1103 (55.5)

2.96 (2.54–3.45)

2.35 (1.97–2.80)

Beliefs: Understand how vaccine works

1228 (84.11)

1405 (70.8)

2.19 (1.85–2.60)

1.55 (1.26–1.92)

Beliefs: Believe vaccines are effective

1333 (91.3)

1600 (80.56)

2.53 (2.05–3.13)

1.91 (1.46–2.48)

Worries: Infertility

134 (9.2)

399 (20.1)

0.40 (0.33–0.50)

0.81 (0.61–1.07)

Worries: Pregnancy loss

255 (17.5)

700 (35.3)

0.39 (0.33–0.46)

0.70 (0.55–0.88)

Worries: Fetal growth and development problems

372 (25.5)

938 (47.2)

0.38 (0.33–0.44)

0.55 (0.43–0.70)

Worries: Child behavioural neurodevelopmental problems

286 (19.6)

745 (37.5)

0.41 (0.35–0.48)

0.59 (0.46–0.75)

Date of survey completiona

  

1.04 (1.04–1.05)

1.04 (1.04–1.05)

B. Pre-conception (n = 447)

Vaccinated

OR (95% CI)

aOR (95% CI)

Variables

Yes = 193

No = 254

  
 

n (%)

n (%)

  

Spoken to HCP about vaccine during perinatal period

104 (53.9)

86 (33.9)

2.28 (1.55–3.35)

2.45 (1.54–3.90)

Beliefs: Understand how vaccine works

168 (87.1)

166 (65.4)

3.56 (2.18–5.83)

1.60 (0.89–2.88)

Beliefs: Believe vaccines are effective

178 (92.2)

192 (75.6)

3.83 (2.10–6.98)

2.56 (1.26–5.20)

Worries: Infertility

50 (25.9)

127 (50.0)

0.35 (0.23–0.52)

0.67 (0.38–1.17)

Worries: Pregnancy loss

65 (33.7)

163 (64.2)

0.28 (0.19–0.42)

0.68 (0.39–1.20)

Worries: Fetal growth and development problems

62 (32.1)

181 (71.3)

0.19 (0.13–0.29)

0.44 (0.24–0.83)

Worries: Child behavioural neurodevelopmental problems

37 (19.2)

143 (56.3)

0.18 (0.12–0.29)

0.47 (0.25–0.89)

Date of survey completion

  

1.02 (1.01–1.03)

1.02 (1.01–1.03)

C. Pregnancy (n = 1832)

Vaccinated

OR (95% CI)

aOR (95% CI)

 

Yes = 770

No = 753

  

Variables

n (%)

n (%)

  

Spoken to HCP about vaccine during perinatal period

714 (92.7)

802 (75.5)

4.13 (3.04–5.61)

2.65 (1.87–3.77)

Beliefs: Understand how vaccine works

655 (85.1)

753 (70.9)

2.33 (1.84–2.97)

1.72 (1.28–2.30)

Beliefs: Believe vaccines are effective

696 (90.4)

862 (81.2)

2.18 (1.64–2.90)

1.44 (1.01–2.07)

Worries: Infertility

38 (4.9)

162 (15.3)

0.29 (0.20–0.42)

0.67 (0.42–1.06)

Worries: Pregnancy loss

145 (18.8)

451 (42.5)

0.31 (0.25–0.39)

0.54 (0.40–0.74)

Worries: Fetal growth and development problems

243 (31.6)

604 (56.9)

0.35 (0.29–0.43)

0.59 (0.43–0.89)

Worries: Child behavioural neurodevelopmental problems

191 (24.8)

471 (44.4)

0.41 (0.34–0.51)

0.62 (0.46–0.85)

Date of survey completion

  

1.04 (1.04–1.05)

1.05 (1.04–1.05)

D. Breastfeeding (n = 1167)

Vaccinated

OR (95% CI)

aOR (95% CI)

 

Yes = 459

No = 670

  

Variables

n (%)

n (%)

  

Spoken to HCP about vaccine during perinatal period

331 (66.6)

215 (32.1)

4.22 (3.30–5.40)

3.48 (2.61–4.63)

Beliefs: Understand how vaccine works

405 (81.5)

486 (72.5)

1.67 (1.26–2.21)

1.17 (0.81–1.70)

Beliefs: Believe vaccines are effective

459 (92.4)

546 (81.5)

2.74 (1.87–4.03)

2.65 (1.61–4.34)

Worries: Infertility

46 (9.26)

110 (16.4)

0.52 (0.36–0.75)

0.59 (0.34–1.01)

Worries: Pregnancy loss

45 (9.1)

86 (12.8)

0.68 (0.46–0.99)

1.92 (1.06–3.49)

Worries: Fetal growth and development problems

67 (13.5)

153 (22.8)

0.53 (0.39–0.72)

0.53 (0.30–0.93)

Worries: Child behavioural neurodevelopmental problems

58 (11.7)

131 (19.6)

0.54 (0.39–0.76)

0.65 (0.37–1.16)

Date of survey completion

  

1.05 (1.04–1.06)

1.05 (1.05–1.06)

  1. aDate of survey completion is entered as a continuous variable to account for variability in the availability of the vaccine or changes to COVID-19 related policies