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Table 1 Characteristics and Findings of Included Studies

From: Structural interventions that affect racial inequities and their impact on population health outcomes: a systematic review

Author, Year

Study Design

Setting

Intervention

Sample size, population

Data Collection Period and Source

Racial or Ethnic Identities

Comparator

Outcome

Findings

Quality

Financial Policies

 Averett, 2012 [39]

Quasi-experimental

USA

Expansion of Earned Income Tax Credit (EITC)

N = 12,686,

Low-to-moderate income mothers

1992–1998, National Longitudinal Survey of Youth 1979 Cohort

Stratified analysis: Black, Hispanic, White

Before and after expansion of EITC

Smoking status

No statistically significant difference in smoking status for Black or Hispanic mothers.

Moderate

 Balan-Cohen, 2008 [40]

Quasi-experimental

USA

Old Age Assistance (OAA)

Total sample size NR; low-income seniors

1927–1955; Vital Statistics Reports

Stratified analysis: Black, White

Non-recipients of OAA

Mortality from treatable illnesses, behavioral causes and cardiovascular disease

Reduced mortality for Black (12%) and White (17%) in non-Southern States. Statistical difference not evaluated.

No statistically significant difference in mortality in Southern States.

Moderate

 Braga, 2020 [41]

Quasi-experimental

USA

Earned Income Tax Credit during childhood

N = 2393, children of low-to-moderate income workers

1968–2017, Panel Study of Income Dynamics

Stratified analysis: Black, Hispanic, other races, White

Differing EITC levels across States

Self-reported overall health, obesity, high blood pressure, functional limitations, emotional problems during adulthood

No statistically significant differences in self-reported health outcomes for Black, Hispanic or other races for different EITC levels.

Moderate

 Bruckner, 2013 [42]

Quasi-experimental

USA

Earned Income Tax Credit

N = 259,480, low-to-moderate income pregnant mothers

1989–1997, California Birth Files

Stratified analysis: Black, White

Non-recipients of EITC

Very low birthweight (< 1500 g) among live singleton births

Odds of very low birthweight increased for Black women when EITC received within 2 months of delivery (OR 1.31, 95%CI 1.09, 1.58). No statistically significant differences for White women or when EITC received earlier in pregnancy.

Moderate

 Cloud, 2019 [43]

Quasi-experimental

USA

State-level minimum wage policies

N = 73 Metropolitan Statistical Areas, each with population > 500,000 residents

2007–2015, CDC HIV name-based reporting system and USA Census Bureau

Primary population: Black

Before and after minimum wage increase

Annual incidence of HIV diagnoses in heterosexual individuals

Metropolitan Statistical Areas with a $1.00 higher minimum wage had a 27.12% (95% CI 18.06, 35.18) lower rate of incident HIV cases in heterosexual Black individuals.

Moderate

 Goldstein, 2020 [44]

Quasi-experimental

USA

Government expenditure on non-healthcare services

Total sample size NR; infants and mothers

2000–2016, US National Center for Health

Statistics

Stratified analysis: Black, Hispanic, Asian, White

Differing levels of state and local government expenditures across States

Infant mortality

No significant difference in the change in infant mortality per increase in government spending for infants born to mothers of different races.

Moderate

 Hoynes, 2015 [45]

Quasi-experimental

USA

Earned Income Tax Credit

N = 17,865, low-to-moderate income pregnant women

1983–1999, Vital Statistics Reports

Stratified analysis: Black, Hispanic, White

Before and after expansion of EITC

Birthweight, low birthweight (< 2500 g)

Reduction in low birthweight incidence for Black women (0.73%, p < 0.01).

Moderate

 Jagannathan, 2010 [46]

RCT

USA

New Jersey Family Development Program (FDP) Welfare Reform

N = 8393, low-income women

1992–1996; primary data

Stratified analysis: Black, Hispanic, White

Welfare recipients not subject to FDP reform

Clinically diagnosed depressive or anxiety disorders

For Black women subject to FDP reform, decreased incidence of anxiety disorder diagnosis (−15.3%, p < 0.05) and depressive disorder diagnosis (− 2.1%, p < 0.05). For Hispanic women subject to FDP reform, increased incidence of depressive disorder diagnosis (68%, p < 0.05)

Moderate

 Komro, 2019 [47]

Quasi-experimental

USA

Earned Income Tax Credit

N = 29,269,997, low-to-moderate income pregnant women

1994–2013, Vital Statistics Reports

Stratified analysis: Black, Hispanic, White

Non-recipients of EITC, differing EITC levels across States, EITC with and without refund

Birthweight, low birthweight (< 2500 g), weeks gestation

Increase in birth weight (16.12–37.16 g, p < 0.01), reduction in incidence of low birthweight (0.6–1.4%, p = 0.0001) and increase in gestational age (0.38–0.46%, p for Black women when receiving EITC. The relative percent changes are not significantly different for White women.

High

 Rosenquist, 2019 [48]

Quasi-experimental

USA

State-level Minimum wage policies

N = 3,869,884, low-income

1980–2010, Vital Statistics Reports

Stratified analysis: Black, White

Different minimum wage levels across States

Infant mortality

Decreased odds of infant mortality for Black women in states with higher minimum wage (adjusted OR 0.80, 95%CI 0.68, 0.94), and in states with greatest increase in minimum wage (adjusted OR 0.89, 95% CI 0.82, 0.96).

Moderate

Nutrition Safeguards

 Arons, 2016 [49]

Quasi-experimental

USA

Special supplemental nutrition program for women, infants, and children (WIC)

N = 327 mother-child dyads

2006–2011, primary data

Stratified analysis: Black

Full sample

Childhood socioemotional development

No significant difference in socioemotional development in Black children whose mothers receive WIC.

Moderate

 Booshehri, 2021 [50]

Quasi-experimental

USA

Special Supplemental Nutrition Program (SNAP) eligibility at 60 years of age

N = 15,980, low-income older adults (age 60–64 years)

2008–2013, Medical Expenditure Panel Survey

Stratified analysis: Black, Hispanic, other races, White

Adults aged 56–59 not yet eligible for SNAP

Diet-related morbidities

Upon reaching SNAP eligibility at age 60, decreased prevalence of hypertension (−13.95%, p < 0.01) for Black individuals, decreased prevalence of angina (−6.94%, p < 0.01) and stroke (−4.48%, p < 0.01) for Hispanic individuals.

Moderate

 Conrad, 2017 [51]

Quasi-experimental

USA

Special Supplemental Nutrition Program (SNAP)

N = 499,741

2000–2011, National Health Interview Survey

Stratified analysis: Black, Hispanic

SNAP-eligible non-participants

All-cause mortality, cardiovascular mortality

Compared to SNAP-eligible non-participants of same race, statistically significant (p < 0.01) higher risk of all-cause and diabetes-related mortality for Black SNAP participants; higher all-cause mortality for Hispanic SNAP participants; higher all-cause, cardiovascular and diabetes-related mortality for White SNAP participants.

Low

 Jia, 2020 [52]

Quasi-experimental

USA

Updated National School Lunch Program (NSLP)

N = 9172, children

2005–2016, National HEalth and Nutrition Examination Survey (NHANES)

Stratified analysis: Black, Hispanic

Before and after update to NSLP

Dietary intake

Black students increased fruit and vegetable intake by 0.27 cups (95% CI = 0.07, 0.46). Hispanic students reduced in weekday fruit and vegetable intake by 0.29 cups (95% CI = -0.50, −0.08).

Moderate

 Kong, 2014 [53]

Quasi-experimental

USA

Revision to Special supplemental nutrition program for women, infants, and children (WIC) to provide more whole grains, fruits, vegetables, and fewer foods with high saturated fat content

N = 295, parent-child dyads

2009–2011, primary data

Stratified analysis: Black, Hispanic

Before and after revisions to WIC

Dietary intake, food group intake, diet quality

No significant changes in nutrient intake and overall diet quality were observed for mothers. Black children increased consumption of sugar-sweetened beverages (p = 0.01). Hispanic children improved in diet quality (p = 0.02) and saturated fat intake (p = 0.0004).

Moderate

Immigration

 Bruzelius, 2019 [54]

Quasi-experimental

USA

National anti-immigration policy changes, increased ICE arrest rates

N = 118,883, adults

2014–2018, Behavioral Risk Factor Surveillance

System (BRFSS)

Primary population: Hispanic or Latinx of any race

Before and after immigration policy changes

Mental health

No significant changes in reports of at least one poor mental health day in preceding month, any indication of poor mental health or reports of frequent mental distress.

High

 Hamilton, 2020 [55]

Quasi-experimental

USA

Deferred Action for Childhood Arrivals (DACA)

N = 72,613, singleton births

2010–2014, National Centre for Health Statistics

Primary population: Hispanic or Latinx of any race

Infants born to DACA-ineligible mothers; before and after DACA enactment

Birthweight, gestational age

For infants born to DACA-eligible mothers and conceived after DACA enactment,

• Low birthweight decreased by 1% (p < 0.05)

• Very low birthweight decreased by 0.4% (p < 0.05)

• Birthweight increased by average 28.8 g (p < 0.01)

• Average gestational age increased by 0.09 weeks (p < 0.05)

Moderate

 Hatzenbuehler, 2017 [56]

Quasi-experimental

USA

State-level exclusionary immigration policies

N = 293,081, adults

2012, Behavioral Risk Factor Surveillance

System (BRFSS)

Primary population: Hispanic or Latinx of any race

States with less exclusionary immigration policies

Mental health

In states with more exclusionary immigration policies, Latinx had 1.14 times (95% CI 1.04,1.25) the rate of poor mental health days than Latinx in states with less exclusionary immigration policies. The association between state immigration policies and rate of poor mental health days higher for Latins than non-Latinx (RR 1.03, 95% CI = 1.01, 1.06).

Moderate

 Potochnick, 2017 [57]

Quasi-experimental

USA

Federal 287(g) program increasing immigration policy enforcement

N = 58,353, adults

2004–2009, Current Population Survey Food Supplement Survey (CPS-FSS)

Primary population: Hispanic or Latinx of any race

Before and after 287(g) enactment

Food security

Enactment of 287(g) was associated with 10.9% (p < 0.01) increase in food insecurity for Mexican non-citizen households with children. No significant effects for Hispanic citizen, non-Hispanic White or non-Hispanic Black households.

Moderate

 Torche, 2019 [58]

Quasi-experimental

USA

Arizona’s Senate Bill SB1070 increasing immigration policy enforcement

N = 1.5 million, mother-child dyads

2007–2012, Centers for Disease Control and Prevention and Arizona Department of Health Services

Primary population: Hispanic or Latinx of any race

Before and after enactment of SB1070

Birthweight, gestational age, birth rate

Following enactment of SB1070, significant decline in birthweight (15 g, p < 0.01) for infants born in late 2010 to immigrant Latina mothers exposed to passage of law during pregnancy.

High

 Vargas, 2017 [59]

Quasi-experimental

USA

State-level exclusionary immigration policies

N = 1200, adults

2011, Latino Decisions/ImpreMedia Survey

Primary population: Hispanic or Latinx of any race

States with less punitive anti-immigration policies

Overall health status

Compared to Latinx respondents in states with more punitive anti-immigration policies, Latinx respondents in states with low or medium punitive anti-immigration laws were more likely to report optimal health (OR 1.8, p ≤ 0.05 and OR 1.5, p ≤ 0.05 for low and medium punitive laws, respectively)

Moderate

 Venkataramani, 2017 [60]

Quasi-experimental

USA

Deferred Action for Childhood Arrivals (DACA)

N = 14,973, adults

2008–2015, US National Health Interview Survey (NHIS)

Primary population: Hispanic or Latinx of any race

DACA-ineligible adults

Overall health, psychological distress

Implementation of DACA associated with significant reductions in psychological distress scores (incident RR 0.78, 95% CI = 0.56, 0.95) and odds of reporting moderate or worse psychological distress (adjusted incident RR 0.62, 95% CI = 0.41, 0.93) for DACA-eligible compared to DACA-ineligible respondents.

Moderate

Family and Reproductive Policies

 Coles, 2010 [61]

Quasi-experimental

USA

Restrictive Abortion Statutes (parental involvement laws, Medicaid funding restrictions, mandatory waiting periods)

N = 8245, adolescents aged 10–17 years

2000–2005, Pregnancy Risk Assessment Monitoring System (PRAMS)

Stratified analysis: Black, Hispanic

States with less restrictive abortion policies

Unwanted or mistimed births. (Mistimed births were reported in cases where the mother wanted pregnancy only later in life)

In states with Medicaid funding restrictions, Black minors had higher rates of mistimed (RR 4.11, p < 0.05) compared to states with no such restrictions.

Low

 Hamad, 2019 [62]

Quasi-experimental

USA

Paid family leave policies

N = 306,266, post partum women

2003–2015, National Immunization Survey

Stratified analysis: Black, Hispanic

Before and after implementation of paid family leave policies

Self-reported breastfeeding at any time and at 3-, 6- and 12-months post-partum

Following implementation of paid family leave policies, Hispanic mothers were 2.3% more likely to report exclusive breastfeeding at 6 months (95% CI = 1.2, 3.4). Black mothers were 3.8% less likely to report breastfeeding at 6 months (95% CI = -7.3, −0.3), 2.9% less likely at 12 months (95% CI = -4.8, −1.0) and reported shorter breastfeeding duration by 15.5 days (95% CI = -24.2, −6.9).

Moderate

 Sudhinaraset, 2020 [63]

Quasi-experimental

USA

Reproductive rights policies

N = 3,945,875, women

2014–2015, National Center for Health Statistics

Stratified analysis: Black, Hispanic, Asian

States with less restrictive abortion policies

Birthweight, preterm birth

In states with the least restrictive rights policies, Black women had a lower risk of low birth weight than Black women in the most restrictive states (Adjusted RR 0.92, 95% CI = 0.86, 0.99)

Moderate

Policies for Indigenous Populations

 Clough, 2017 [64]

Quasi-experimental

Australia

Alcohol Management Plans (AMPs)

N = 1211, adults in Queensland’s remote Indigenous communities

2014–2015, primary data

Primary population: Aboriginal and Torres Strait Islanders

Before and after implementation of AMPs

“Favourable” and “unfavourable” alcohol-related health outcomes in the community

Majority of respondents agreed that AMPs made communities safer and less violent. Majority of respondents reported more cannabis use and binge drinking, that alcohol was no less available, and that more law enforcement activities such as fines and arrests occurred.

Moderate

 Feir, 2015 [65]

Quasi-experimental

Canada

Residential school system

N = 4939, First Nations, Métis or Inuit children

2001, Aboriginal Peoples Survey of Children and Youth (APSCY)

Primary population: First Nations, Métis or Inuit children

Children whose mothers did not attend residential schools

BMI, height, birthweight, childhood injuries

Children whose mothers attended residential school had higher average BMI (p < 0.05) than children whose mothers did not attend residential school.

Moderate

 Larson, 2019 [66]

Quasi-experimental

Australia

Indigenous land and sea management programs (ILSMPs)

N = 190 Ewamian people, Nyikina Mangala, Bunuba people and Walmajarri people

Time period NR, primary data

Primary population: Aboriginal and Torres Strait Islanders

Before and after implementation of ILSMPs

Holistic wellbeing impact evaluation (W-IE)

After implementation of ILSMPs, respondents reported positive change in satisfaction for following wellbeing factors

• “Country looked after” (health of land)

• Information and communications technology

• Legal right to country

• Business ownership

A negative change in satisfaction was reported for consuming traditional foods.

Low

Environmental

 Furzer, 2020 [67]

Quasi-experimental

USA

Environmental Policy: PM 2.5 and Clean Air Act Regulations

Not applicable

2000–2016, primary data and 2020, Johns Hopkins University Coronavirus Resource

Center

Primary population: Black, minority

Regions without air pollution limit attainment

COVID-19 deaths

Counties with high proportion of Black or minority residents are less likely to attain air pollution limits, with 6.8–16% more COVID-19 deaths for Black or minority residents.

Moderate

  1. CI Confidence Interval, OR Odds Ratio, RR Risk ratio, NR Not reported, BMI Body Mass Index, PM Particulate Matter