From: Spatial-temporal trends in the risk of illicit drug toxicity death in British Columbia
 | Unadjusted | Adjusted | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Variable | OR1 | 95% CI1 | p-value | OR2 | 95% CI | p-value | OR3 | 95% CI | p-value | OR4 | 95% CI | p-value |
Urbanicity | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Large | – | – |  | – | – |  | – | – |  | – | – |  |
Medium | 1.14 | 1.04, 1.24 | 0.003 | 1.27 | 1.10, 1.47 | 0.001 | 1.16 | 1.00, 1.34 | 0.057 | 1.14 | 0.98, 1.32 | 0.090 |
Small | 1.29 | 1.16, 1.43 | < 0.001 | 1.22 | 1.01, 1.47 | 0.035 | 1.06 | 0.88, 1.29 | 0.5 | 1.03 | 0.85, 1.24 | 0.8 |
Rural | 1.59 | 1.42, 1.78 | < 0.001 | 1.57 | 1.29, 1.91 | < 0.001 | 1.36 | 1.11, 1.66 | 0.003 | 1.31 | 1.07, 1.60 | 0.009 |
Location Type | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Private | – | – |  |  |  |  | – | – |  | – | – |  |
Public Buildings | 0.07 | 0.06, 0.09 | < 0.001 |  |  |  | 0.08 | 0.06, 0.09 | < 0.001 | 0.08 | 0.06, 0.09 | < 0.001 |
Healthcare Facilities | 0.18 | 0.14, 0.25 | < 0.001 |  |  |  | 0.18 | 0.13, 0.25 | < 0.001 | 0.19 | 0.14, 0.27 | < 0.001 |
Outdoor | 0.15 | 0.14, 0.17 | < 0.001 |  |  |  | 0.16 | 0.14, 0.18 | < 0.001 | 0.16 | 0.15, 0.18 | < 0.001 |
Others | 0.58 | 0.52, 0.66 | < 0.001 |  |  |  | 0.62 | 0.54, 0.70 | < 0.001 | 0.65 | 0.57, 0.75 | < 0.001 |
Recurrent Event | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
No | – | – |  | – | – |  |  |  |  | – | – |  |
Yes | 0.51 | 0.48, 0.55 | < 0.001 | 0.52 | 0.48, 0.56 | < 0.001 |  |  |  | 0.60 | 0.56, 0.65 | < 0.001 |
Age | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
18–29 | – | – |  | – | – |  | – | – |  | – | – |  |
< 18 | 0.53 | 0.38, 0.75 | < 0.001 | 0.50 | 0.36, 0.71 | < 0.001 | 0.57 | 0.41, 0.81 | 0.002 | 0.54 | 0.38, 0.76 | < 0.001 |
30–49 | 1.78 | 1.63, 1.93 | < 0.001 | 1.73 | 1.59, 1.89 | < 0.001 | 1.72 | 1.57, 1.88 | < 0.001 | 1.68 | 1.54, 1.83 | < 0.001 |
50–64 | 2.92 | 2.65, 3.21 | < 0.001 | 2.71 | 2.45, 2.99 | < 0.001 | 2.41 | 2.17, 2.67 | < 0.001 | 2.30 | 2.07, 2.54 | < 0.001 |
≥65 | 3.13 | 2.70, 3.63 | < 0.001 | 2.76 | 2.37, 3.22 | < 0.001 | 2.48 | 2.11, 2.92 | < 0.001 | 2.24 | 1.91, 2.64 | < 0.001 |
Sex | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
F | – | – |  | – | – |  | – | – |  | – | – |  |
M | 1.61 | 1.49, 1.74 | < 0.001 | 1.62 | 1.50, 1.75 | < 0.001 | 1.77 | 1.64, 1.92 | < 0.001 | 1.81 | 1.67, 1.96 | < 0.001 |
Benzodiazepines Prescriptions | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
No | – | – |  | – | – |  | – | – |  | – | – |  |
Yes | 1.46 | 1.30, 1.63 | < 0.001 | 1.43 | 1.26, 1.63 | < 0.001 | 1.37 | 1.20, 1.57 | < 0.001 | 1.37 | 1.20, 1.56 | < 0.001 |
Other Sedatives Prescriptions | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
No | – | – |  | – | – |  | – | – |  | – | – |  |
Yes | 1.19 | 1.11, 1.28 | < 0.001 | 0.89 | 0.81, 0.96 | 0.005 | 0.86 | 0.79, 0.94 | < 0.001 | 0.88 | 0.81, 0.96 | 0.004 |
Opioids for pain Prescriptions | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
No | – | – |  | – | – |  | – | – |  | – | – |  |
Yes | 1.54 | 1.38, 1.73 | < 0.001 | 1.14 | 1.00, 1.30 | 0.054 | 1.05 | 0.92, 1.21 | 0.5 | 1.04 | 0.91, 1.19 | 0.6 |
Social Deprivation | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Q3 | – | – |  | – | – |  | – | – |  | – | – |  |
Q1 | 1.20 | 1.05, 1.37 | 0.008 | 1.28 | 1.12, 1.46 | < 0.001 | 1.24 | 1.08, 1.43 | 0.002 | 1.22 | 1.06, 1.40 | 0.004 |
Q2 | 1.05 | 0.93, 1.18 | 0.5 | 1.08 | 0.95, 1.22 | 0.2 | 1.12 | 0.98, 1.27 | 0.092 | 1.12 | 0.99, 1.27 | 0.083 |
Q4 | 1.00 | 0.89, 1.12 | > 0.9 | 0.99 | 0.88, 1.11 | 0.9 | 0.98 | 0.87, 1.11 | 0.8 | 1.00 | 0.88, 1.12 | > 0.9 |
Q5 | 0.96 | 0.87, 1.06 | 0.4 | 0.96 | 0.87, 1.06 | 0.4 | 0.97 | 0.87, 1.07 | 0.5 | 1.00 | 0.90, 1.11 | > 0.9 |
Year | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
2015–2016 | – | – |  | – | – |  | – | – |  | – | – |  |
2017–2018 | 1.26 | 1.19, 1.34 | < 0.001 | 1.40 | 1.29, 1.52 | < 0.001 | 1.29 | 1.19, 1.41 | < 0.001 | 1.39 | 1.28, 1.52 | < 0.001 |
Urbanicity * Year | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Medium * 2017–2018 |  |  |  | 0.86 | 0.72, 1.03 | 0.11 | 0.91 | 0.76, 1.10 | 0.3 | 0.91 | 0.75, 1.09 | 0.3 |
Small * 2017–2018 |  |  |  | 1.07 | 0.86, 1.35 | 0.5 | 1.08 | 0.85, 1.36 | 0.5 | 1.05 | 0.83, 1.33 | 0.7 |
Rural * 2017–2018 |  |  |  | 0.89 | 0.70, 1.14 | 0.4 | 0.92 | 0.72, 1.19 | 0.5 | 0.90 | 0.70, 1.15 | 0.4 |