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Table 8 Proof of concept for the framework. We applied the COS criteria for outcomes on work participation (Table 3) to the work outcomes used in 6 RCTs with different health conditions and heterogeneous disability trajectories. We compared the extent to which work participation outcomes in RCTs met the 8 COS criteria

From: A general framework for selecting work participation outcomes in intervention studies among persons with health problems: a concept paper

Participants; Health condition

Participants; employment status at inclusion

Work participation stage

Intervention

Measured work participation outcomes

Fit with mandatory criteria

Fit with optional criteria

1

2

3

4

5

6

7

8

Schizophrenia [96]

Unemployed

Initiating employment, Having employment

Vocational rehabilitation

-Frequency of job interviews,

-Work status,

-Worked hours

x

x

x

x

x

x

 

x

Rheumatoid arthritis [97]

40% employed

Increasing or maintaining productivity at work

Pharmaceutical

-Work productivity

x

x

x

x

x

x

 

x

Depression [98]

83% employed

Return to employment

Using self-assessment of depression course during GP consultations

-Work ability, −Sick leave,

-Time to return to work

x

x

x

x

x

x

x

x

Breast cancer [99]

Unspecified

Return to employment

Post radiation exercise program

-Return to work (sick leave)

x

x

x

x

x

x

x

x

Influenza [100]

100% employed

Return to employment

Vaccination against influenza

-Sick leave

x

x

x

x

x

x

x

x

On sick leave for at least 6 months due to any health problem [101]

Employed

Return to employment

Independent medical evaluation

-Sick leave

x

x

x

x

x

x

x

x

  1. Legend: COS criteria: Mandatory criteria 1: be sensitive to change; 2: be feasible to measure; 3: be applicable internationally; 4: be work participation specific; 5: capture multiple stakeholder perspectives; 6: be in alignment with the ICF model. Optional criteria 7: be used for cost-effectiveness studies; 8: be applicable across different insurance schemes