MomsTalkShots, tailored educational app, improves vaccine attitudes: a randomized controlled trial

Dudley, Matthew Z.; Omer, Saad B.; O’Leary, Sean T.; Limaye, Rupali J.; Ellingson, Mallory K.; Spina, Christine I.; Brewer, Sarah E.; Bednarczyk, Robert A.; Chamberlain, Allison T.; Malik, Fauzia; Frew, Paula M.; Church-Balin, Cathy; Riley, Laura E.; Ault, Kevin A.; Orenstein, Walter A.; Halsey, Neal A.; Salmon, Daniel A.

doi:10.1186/s12889-022-14498-7

BMC Public Health

Table 3 Impact of MomsTalkShots on vaccine KAB constructs of women one year after their infant’s birth stratified by baseline vaccine intentions^a, dichotomous analysis^b

From: MomsTalkShots, tailored educational app, improves vaccine attitudes: a randomized controlled trial

	% with above average construct scores^c among those not receiving MomsTalkShots				% with above average construct scores^c among those receiving MomsTalkShots				Effect of MomsTalkShots on % with above average construct scores^c, OR (95% CI)^b
Intentions to Vaccinate^a	All	Yes	No	Unsure	All	Yes	No	Unsure	All	Yes	No	Unsure
KAB Constructs^c
Specific safety concerns (for infant vaccines)^d	47	39	83	91	44	38	93	71	0.88 (0.67–1.15)	0.93 (0.70–1.25)	2.78 (0.67–11.46)	0.24 (0.06–0.98)
Perceived risk (infant whooping cough)	46	49	26	24	39	40	19	44	0.89 (0.66–1.21)	0.89 (0.64–1.22)	0.53 (0.13–2.27)	1.05 (0.27–4.08)
Pro-vaccine social norms	49	54	22	21	55	59	21	38	1.23 (0.95–1.58)	1.22 (0.93–1.61)	0.67 (0.23–1.94)	2.13 (0.70–6.53)
Perceived vaccine knowledge	50	55	29	12	62	65	40	47	1.74 (1.36–2.24)	1.60 (1.22–2.10)	1.71 (0.73–4.01)	6.89 (1.52–31.25)
Trust in vaccine information (from obstetricians and pediatricians)	55	63	16	15	64	70	14	41	1.53 (1.17–2.00)	1.47 (1.09–1.97)	1.07 (0.32–3.55)	3.41 (1.03–11.29)
Trust in vaccine information (from naturopaths and chiropractors)	53	50	62	65	56	56	57	59	1.04 (0.68–1.60)	1.06 (0.66–1.72)	0.89 (0.22–3.62)	0.90 (0.18–4.63)
Trust in vaccine information (from federal agencies and academic institutions)	51	58	14	12	54	59	12	32	1.30 (0.99–1.71)	1.21 (0.90–1.62)	0.93 (0.27–3.24)	3.03 (0.82–11.12)

^aAll constructs in this table are either relevant to both maternal and infant vaccines or specific to infant diseases or vaccines, so intentions to vaccinate refer to intending to receive all recommended infant vaccines versus intending to receive some or no recommended infant vaccines
^bOR = Odds Ratio from logistic regression comparing the proportions with above average construct scores^c at follow-up between those receiving MomsTalkShots and those not receiving MomsTalkShots, controlling for the corresponding proportions with above average construct scores^c at baseline; 95%CI = 95% Confidence Interval; bolded if statistically significant (in the dichotomous analysis)
^cKAB = knowledge, attitudes, and beliefs. Summary scores were created for all KAB constructs with multiple constituent survey statements at each timepoint (see Additional file 1: Appendix 2). Dichotomous variables assessing construct summary scores coded scores above the average as 1 and scores below the average as 0. Constructs assessing KAB about maternal disease and vaccines were not assessed in the final survey one year after birth
^dThe KAB construct “Specific safety concerns (for infant vaccines)” was created from negatively phrased survey statements, so a negative association would indicate a positive effect on vaccine perceptions. All other KAB constructs in this table were created from positively phrased survey statements, so a positive association would indicate a positive effect on vaccine perceptions

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ISSN: 1471-2458

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