| Spouse pairs (Reported in our earlier study) [20] | Random male-female pairs (Exact age-match of spouse pairs) | ||||||
---|---|---|---|---|---|---|---|---|
 | Number of pairs | Husband | Wife |  p-value | Number of pairs | Male | Female | p-value |
General characteristics | Â | Â | Â | Â | Â | Â | Â | Â |
Mean age at baseline, years (SD) | 5,391 | 63.2 (10.5) | 60.4 (10.2) | < 0.001 | 5,391 | 63.2 (10.5) | 60.4 (10.2) | < 0.001 |
Age group, years | 5,391 |  |  | < 0.001 | 5,391 |  |  | < 0.001 |
 20–39, n (%) |  | 293 (5.4%) | 346 (6.4%) |  |  | 293 (5.4%) | 346 (6.4%) |  |
 40–59, n (%) |  | 931 (17.3%) | 1,373 (25.5%) |  |  | 931 (17.3%) | 1,373 (25.5%) |  |
 60–69, n (%) |  | 2,678 (49.7%) | 2,995 (55.6%) |  |  | 2,678 (49.7%) | 2,995 (55.6%) |  |
 ≥70, n (%) |  | 1,489 (27.6%) | 677 (12.6%) |  |  | 1,489 (27.6%) | 677 (12.6%) |  |
Education level | 5,254 |  |  | < 0.001  | 5,245 |  |  | < 0.001 |
 Low, n (%) |  | 643 (12.2%) | 443 (8.4%) |  |  | 643 (12.3%) | 440 (8.4%) |  |
 Medium, n (%) |  | 3,141 (59.8%) | 3,884 (73.9%) |  |  | 3,140 (59.9%) | 3,884 (74.1%) |  |
 High, n (%) |  | 1,470 (28.0%) | 927 (17.6%) |  |  | 1,462 (27.9%) | 921 (17.6%) |  |
Risk factors | Â | Â | Â | Â | Â | Â | Â | Â |
Mean weight, kg (SD) | 5,390 | 66.5 (9.6) | 54.1 (8.7) | < 0.001 | 5,385 | 66.4 (9.5) | 54.1 (8.7) | < 0.001 |
Mean height, cm (SD) | 5,391 | 166.7 (6.0) | 154.3 (5.6) | < 0.001 | 5,391 | 166.7 (6.0) | 154.4 (5.6) | < 0.001 |
Mean waist circumference, cm (SD) | 3,183 | 85.6 (8.2) | 81.9 (9.2) | < 0.001 | 2,143 | 85.6 (8.1) | 82.0 (9.0) | < 0.001 |
Mean body mass index, kg/m2 (SD) | 5,198 | 23.9 (3.0) | 22.7 (3.5) | < 0.001 | 5,009 | 23.9 (3.0) | 22.7 (3.5) | < 0.001 |
Mean SBP, mmHg (SD) | 5,106 | 129.7 (16.3) | 125.9 (17.7) | < 0.001 | 4,840 | 129.7 (16.3) | 125.9 (17.6) | < 0.001 |
Mean DBP, mmHg (SD) | 5,106 | 78.9 (10.6) | 75.2 (10.6) | < 0.001 | 4,841 | 78.9 (10.6) | 75.2 (10.5) | < 0.001 |
Mean HbA1c, % (SD) | 4,602 | 5.5 (0.5) | 5.5 (0.4) | 0.39 | 4,568 | 5.5 (0.4) | 5.5 (0.3) | 0.45 |
Mean total cholesterol, mg/dL (SD) | 1,964 | 201.5 (33.5) | 213.7 (35.9) | < 0.001 | 841 | 202.2 (33.6) | 211.7 (36.2) | < 0.001 |
Median triglycerides, mg/dL [IQR, 25th, 75th] | 5,384 | 104 [75–151] | 88 [64–121] | < 0.001 | 5,307 | 107 [76–155] | 91 [65–127] | < 0.001 |
Mean HDL-C, mg/dL (SD) | 5,384 | 57.0 (14.5) | 66.5 (15.5) | < 0.001 | 5,375 | 57.0 (14.4) | 66.5 (15.5) | < 0.001 |
Mean LDL-C, mg/dL (SD) | 3,191 | 118.9 (29.8) | 128.1 (30.4) | < 0.001 | 2,143 | 125.8 (33.7) | 136.9 (33.6) | < 0.001 |
Lifestyle factors | Â | Â | Â | Â | Â | Â | Â | Â |
Smoking status | 5,313 |  |  | < 0.001 | 5,313 |  |  | < 0.001 |
 Currently a smoker, n (%) |  | 1,104 (20.8%) | 248 (4.7%) |  |  | 1,101 (20.7%) | 248 (4.7%) |  |
 Smoker in the past, n (%) |  | 3,066 (57.7%) | 670 (12.6%) |  |  | 3,073 (57.8%) | 671 (12.6%) |  |
 Never smoked, n (%) |  | 1,143 (21.5%) | 4,395 (82.7%) |  |  | 1,139 (21.4%) | 4,394 (82.7%) |  |
Alcohol consumption status | 5,356 |  |  | < 0.001 | 5,354 |  |  | < 0.001 |
 Currently a drinker, n (%) |  | 4,201 (78.4%) | 2,187 (40.8%) |  |  | 4,195 (78.4%) | 2,186 (40.8%) |  |
 Drinker in the past, n (%) |  | 196 (3.7%) | 71 (1.3%) |  |  | 198 (3.7%) | 70 (1.3%) |  |
 Never a drinker, n (%) |  | 959 (17.9%) | 2,558 (47.8%) |  |  | 961 (17.9%) | 3,098 (57.9%) |  |
Sufficient physical activity (≥ 80th percentile of men’s MET hours/day) | 5,342 | 1,074 (20.1%) | 549 (10.3%) | < 0.001 | 5,318 | 1,063 (20.0%) | 548 (10.3%) | < 0.001 |
Hypertension, n (%) | 4,260 | 2,411 (56.6%) | 1,770 (41.6%) | < 0.001 | 4,037 | 2,271 (56.3%) | 1,719 (42.6%) | < 0.001 |
Type 2 diabetes, n (%) | 3,469 | 504 (14.5%) | 246 (7.1%) | < 0.001 | 3,355 | 501 (14.9%) | 240 (7.2%) | < 0.001 |
Metabolic syndrome, n (%) | 3,770 | 1,565 (41.5%) | 1,026 (27.2%) | < 0.001 | 3,697 | 1,501 (40.6%) | 1,014 (27.4%) | < 0.001 |