| Women | Men | ||||
---|---|---|---|---|---|---|
Control | Intervention | RR (CI) | Control | Intervention | RR (CI) | |
n = 850 | n = 213 | n = 154 | n = 39 | |||
Retrieved PCC-Information | ||||||
 Yes | 496 (60.6) | 132 (63.5) | 1.05 (0.93–1.18) | 68 (46.6) | 14 (37.8) | 0.81 (0.52–1.27) |
 No | 323 (39.4) | 76 (36.5) | 78 (53.4) | 23 (62.2) | ||
 Missing data | 31 | 5 | 8 | 2 | ||
Visited PCC-Consultation | ||||||
 Yes | 204 (24.5) | 60 (28.3) | 1.15 (0.90–1.48) | 36 (23.4) | 7 (17.9) | 0.77 (0.37–1.59) |
 No | 628 (75.5) | 152 (71.7) | 118 (76.6) | 32 (82.1) | ||
 Missing data | 18 | 1 | 0 | 0 | ||
Fruit intake | ||||||
 Adequate (≥ 2 pieces) | 203 (25.0) | 54 (25.7) | 1.03 (0.79–1.33) |  |  |  |
 Inadequate (< 2 pieces) | 610 (75.0) | 156 (74.3) |  |  |  | |
 Missing data | 37 | 3 |  |  |  | |
Vegetable intake | ||||||
 Adequate (≥ 250 grams) | 49 (6.0) | 23 (11.0) | 1.82 (1.14–2.91) |  |  |  |
 Inadequate (< 250 grams) | 764 (94.0) | 187 (89.0) |  |  |  | |
 Missing data | 37 | 3 |  |  |  | |
Caffeine intake | ||||||
 Adequate (≤ 2 beverages) | 403 (49.6) | 98 (46.7) | 0.94 (0.80–1.11) |  |  |  |
 Inadequate (> 2 beverages) | 410 (50.4) | 112 (53.3) |  |  |  | |
 Missing data | 37 | 3 |  |  |  | |
Preconceptional nutritiona | ||||||
  ≥ 2 adequate nutrition intakes | 119 (14.6) | 38 (18.1) | 1.24 (0.89–1.72) |  |  |  |
  < 2 adequate nutrition intakes | 694 (85.4) | 172 (81.9) |  |  |  | |
 Missing data | 37 | 3 |  |  |  | |
Folic acid supplements | ||||||
 Started in time (≥ 4 weeks before conception) | 482 (59.5) | 121 (57.6) | 0.97 (0.85–1.10) |  |  |  |
 Started too late or never | 328 (40.5) | 89 (42.4) |  |  |  | |
 Missing data | 40 | 3 |  |  |  | |
Alcohol use | ||||||
 Adequate (no preconceptional alcohol use) | 415 (51.3) | 108 (52.7) | 1.03 (0.89–1.19) | 52 (33.8) | 14 (35.9) | 1.06 (0.66–1.71) |
 Inadequate (used alcohol after conception) | 394 (48.7) | 97 (47.3) | 102 (66.2) | 25 (64.1) | ||
 Missing data | 41 | 8 | 0 | 0 | ||
Change in alcohol useb | ||||||
 Quit before conception | 130 (24.8) | 36 (27.1) | 1.09 (0.80–1.50) | 11 (9.7) | 5 (16.7) | 1.71 (0.64–4.55) |
 Quit after conception / still uses alcohol | 394 (75.2) | 97 (72.9) | 102 (90.3) | 25 (83.3) | ||
 Missing data | 326 | 80 | 41 | 9 | ||
Smoking | ||||||
 Adequate (no preconceptional smoking) | 712 (87.7) | 183 (87.1) | 0.99 (0.94–1.05) | 142 (92.2) | 35 (89.7) | 0.97 (0.88–1.09) |
 Inadequate (smoked after conception) | 100 (12.3) | 27 (12.9) | 12 (7.8) | 4 (10.3) | ||
 Missing data | 38 | 3 | 0 | 0 | ||
Change in smokingb | ||||||
 Quit before conception | 11 (9.9) | 4 (12.9) | 1.30 (0.44–3.81) | 8 (40.0) | 4 (50.0) | 1.25 (0.52–3.00) |
 Quit after conception / still smokes | 100 (90.1) | 27 (87.1) | 12 (60.0) | 4 (50.0) | ||
 Missing data | 739 | 128 | 134 | 31 | ||
Adherence to lifestyle recommendationsc | ||||||
 Adequate | 305 (37.5) | 83 (39.5) | 1.05 (0.87–1.27) | 48 (31.2) | 13 (33.3) | 1.07 (0.65–1.77) |
 Inadequate | 508 (62.5) | 127 (60.5) | 106 (68.8) | 26 (66.7) | ||
 Missing data | 37 | 3 | 0 | 0 |