Hypercholesterolemia (≥ 240 mg/dL) | Hypertriglyceridemia (≥ 200 mg/dL) | Low level of HDL-C (< 40 mg/dL for males and < 50 mg/dL for females) | aHigh level of LDL-C (≥ 130 mg/dL) | |||||
---|---|---|---|---|---|---|---|---|
Unadjusted | Adjusted | Unadjusted | Adjusted | Unadjusted | Adjusted | Unadjusted | Adjusted | |
Urinary ttMA | ||||||||
Q1 | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. |
Q2 | 1.269 (0.805–2.001) | 1.194 (0.745–1.919) | 1.610 (1.233–2.101) | 1.433 (1.107–1.856) | 1.093 (0.821–1.455) | 1.047 (0.771–1.422) | 0.827 (0.568–1.204) | 0.774 (0.528–1.134) |
Q3 | 0.857 (0.546–1.345) | 0.867 (0.556–1.353) | 1.547 (1.164–2.055) | 1.397 (1.037–1.881) | 0.852 (0.641–1.133) | 0.813 (0.605–1.092) | 0.692 (0.485–0.987) | 0.681 (0.475–0.976) |
Q4 | 0.886 (0.580–1.403) | 0.878 (0.545–1.417) | 1.750 (1.383–2.213) | 1.599 (1.231–2.077) | 1.035 (0.758–1.414) | 1.069 (0.771–1.482) | 0.637 (0.439–0.925) | 0.654 (0.446–0.961) |
p for trend | 0.158 | 0.215 | 0.055 | 0.087 | 0.676 | 0.953 | 0.017 | 0.053 |
Urinary BMA | ||||||||
Q1 | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. |
Q2 | 1.025 (0.654–1.607) | 1.013 (0.657–1.561) | 1.128 (0.857–1.484) | 1.486 (1.105–1.998) | 1.065 (0.796–1.425) | 0.906 (0.678–1.212) | 0.841 (0.612–1.155) | 0.806 (0.581–1.119) |
Q3 | 0.817 (0.499–1.336) | 0.753 (0.460–1.230) | 1.195 (0.891–1.604) | 1.579 (1.129–2.208) | 1.124 (0.835–1.514) | 0.780 (0.589–1.033) | 0.736 (0.516–1.050) | 0.619 (0.430–0.889) |
Q4 | 0.809 (0.490–1.334) | 0.770 (0.459–1.294) | 0.989 (0.722–1.353) | 1.338 (0.946–1.894) | 1.258 (0.962–1.646) | 0.812 (0.623–1.058) | 0.785 (0.533–1.154) | 0.668 (0.440–1.015) |
p for trend | 0.241 | 0.192 | 0.559 | 0.821 | 0.088 | 0.180 | 0.398 | 0.109 |
aParticipants with TG levels > 400 mg/dL were excluded from LDL-C analysis (n = 3230). Adjusted model was adjusted for age, sex, BMI, education level, marital status, household income level, smoking, alcohol consumption, and exercise. ttMA, trans,trans-muconic acid; BMA, benzylmercapturic acid; HDL-C, high-density lipoprotein; LDL-C, low-density lipoprotein; TG: triglyceride |