Table 2 Prevalence of early-onset colorectal cancer in 1990 and 2019 for both sexes and all locations, with AAPC from 2009 and 2019
Location | 1990 | 2019 | AAPC % (95% CI) 1990–2019 | ||
|---|---|---|---|---|---|
Cases (95% UI) | Age-standardized prevalence per 100 000 population (95% UI) | Cases (95% UI) | Age-standardized prevalence per 100 000 population (95% UI) | ||
Global | 529,611 (503,694 to 558,749) | 16.31 (15.53 to 17.18) | 1,427,386 (1,303,987 to 1,565,205) | 25.44 (23.24 to 27.9) | 1.43 (1.34 to 1.52) |
Sex | |||||
 Female | 246,208 (230,432 to 263,775) | 15.46 (14.5 to 16.53) | 553,203 (496,575 to 613,615) | 19.87 (17.83 to 22.04) | 0.87 (0.77 to 0.97) |
 Male | 283,403 (265,564 to 303,470) | 17.13 (16.09 to 18.32) | 874,183 (770,140 to 991,423) | 30.93 (27.26 to 35.07) | 1.96 (1.88 to 2.04) |
SDI | |||||
 High SDI | 214,756 (207,303 to 223,108) | 34.96 (33.75 to 36.32) | 340,974 (310,697 to 373,998) | 43.95 (40.06 to 48.19) | 0.8 (0.76 to 0.84) |
 High-middle SDI | 152,777 (142,896 to 164,317) | 20.03 (18.75 to 21.51) | 464,512 (408,620 to 527,879) | 39.44 (34.69 to 44.83) | 2.22 (2.08 to 2.35) |
 Middle SDI | 113,948 (102,702 to 126,258) | 10.84 (9.79 to 11.99) | 465,421 (407,688 to 531,004) | 25.03 (21.94 to 28.55) | 2.91 (2.77 to 3.05) |
 Low-middle SDI | 37,075 (32,378 to 42,183) | 5.9 (5.17 to 6.69) | 123,181 (109,234 to 138,301) | 10.29 (9.13 to 11.55) | 1.93 (1.71 to 2.15) |
 Low SDI | 10,813 (8791 to 13,121) | 4.15 (3.39 to 5.03) | 32,707 (27,851 to 38,179) | 5.43 (4.63 to 6.32) | 0.92 (0.84 to 0.99) |
Region | |||||
 High-income Asia Pacific | 53,158 (49,928 to 56,609) | 37.94 (35.62 to 40.43) | 68,628 (57,781 to 80,329) | 44.92 (37.87 to 52.56) | 0.48 (0.04 to 0.92) |
 High-income North America | 81,814 (77,945 to 85,789) | 39.2 (37.36 to 41.09) | 133,964 (115,141 to 155,811) | 51.94 (44.67 to 60.39) | 0.99 (0.69 to 1.28) |
 Western Europe | 87,816 (83,642 to 92,408) | 31.33 (29.84 to 32.98) | 122,930 (105,229 to 143,136) | 37.44 (32.07 to 43.56) | 0.47 (0.41 to 0.54) |
 Australasia | 6361 (5728 to 7068) | 42.24 (38.05 to 46.93) | 11,186 (8420 to 14,923) | 51.94 (39.05 to 69.28) | 1.03 (0.79 to 1.27) |
 Andean Latin America | 1855 (1528 to 2260) | 8.66 (7.18 to 10.49) | 9822 (7074 to 13,299) | 22.17 (15.96 to 30.02) | 3.24 (2.99 to 3.49) |
 Tropical Latin America | 9166 (8583 to 9780) | 9.85 (9.23 to 10.5) | 32,157 (29,553 to 34,900) | 18.58 (17.07 to 20.17) | 2.2 (2.14 to 2.26) |
 Central Latin America | 7443 (7014 to 7905) | 8.06 (7.61 to 8.55) | 34,236 (28,862 to 40,740) | 19.06 (16.07 to 22.67) | 3.01 (2.94 to 3.08) |
 Southern Latin America | 4870 (4360 to 5421) | 15.14 (13.57 to 16.85) | 13,306 (9786 to 17,659) | 27.11 (19.94 to 35.97) | 2.09 (1.94 to 2.23) |
 Caribbean | 3087 (2760 to 3439) | 14.44 (12.94 to 16.05) | 7094 (5703 to 8726) | 21.08 (16.94 to 25.94) | 1.38 (1.3 to 1.45) |
 Central Europe | 20,608 (19,426 to 21,852) | 23.64 (22.28 to 25.07) | 30,611 (26,065 to 35,706) | 33.17 (28.25 to 38.69) | 1.14 (0.96 to 1.32) |
 Eastern Europe | 37,800 (34,828 to 40,408) | 25.16 (23.19 to 26.88) | 58,171 (50,829 to 66,416) | 35.17 (30.73 to 40.14) | 1.43 (0.82 to 2.04) |
 Central Asia | 6441 (5943 to 6961) | 17.09 (15.79 to 18.43) | 10,080 (8735 to 11,586) | 15.13 (13.12 to 17.39) | -0.65 (-1.01 to -0.3) |
 North Africa and Middle East | 14,531 (11,807 to 18,127) | 8.05 (6.56 to 10.02) | 63,316 (53,915 to 74,129) | 14.01 (11.93 to 16.41) | 1.88 (1.75 to 2.01) |
 South Asia | 25,424 (21,799 to 29,403) | 4.03 (3.48 to 4.65) | 83,288 (70,439 to 97,088) | 6.69 (5.66 to 7.79) | 1.79 (1.63 to 1.95) |
 Southeast Asia | 27,997 (23,690 to 31,899) | 10.37 (8.83 to 11.79) | 100,248 (82,096 to 120,522) | 19.38 (15.88 to 23.3) | 2.14 (2.09 to 2.2) |
 East Asia | 130,021 (112,991 to 149,447) | 15.75 (13.7 to 18.08) | 615,021 (512,753 to 726,748) | 49.73 (41.55 to 58.68) | 4.04 (3.83 to 4.25) |
 Oceania | 271 (210 to 347) | 7.47 (5.82 to 9.55) | 744 (545 to 1020) | 8.72 (6.39 to 11.95) | 0.53 (0.46 to 0.61) |
 Western Sub-Saharan Africa | 3319 (2622 to 4118) | 3.49 (2.76 to 4.33) | 11,238 (8863 to 13,819) | 4.7 (3.72 to 5.77) | 1.05 (0.96 to 1.14) |
 Eastern Sub-Saharan Africa | 4044 (3199 to 5010) | 4.66 (3.71 to 5.76) | 12,953 (10,445 to 16,051) | 6.1 (4.94 to 7.55) | 0.92 (0.88 to 0.96) |
 Central Sub-Saharan Africa | 1119 (782 to 1565) | 4.29 (3.02 to 5.98) | 3264 (2278 to 4578) | 4.77 (3.34 to 6.67) | 0.36 (0.31 to 0.4) |
 Southern Sub-Saharan Africa | 2466 (2121 to 2845) | 8.63 (7.46 to 9.9) | 5130 (3942 to 6498) | 9.39 (7.25 to 11.87) | 0.28 (0.08 to 0.48) |