Table 1 Lessons learned from the implementation of a mail-based SARS-CoV-2 serosurvey

• A small test batch of boxes should be sent out before sending to all participants to identify problems with the sample collection kit.

• The logistics of navigating the supply chain, package assembly, and shipping can be challenging and should be carefully planned.

• Professional shipping support for 2-way discrete packages is essential.

• Study participation may be increased by sending out survey invitations from a familiar on-campus office.

• A stratified sampling approach for participant selection may better characterize disease transmission in the broader population.

• Pilot testing the initial survey may prevent confusion with study enrollment

• Ensuring sample-to-record linkages in remote settings requires careful consideration.

• Processes for return shipment need to be as user-friendly as possible.

• Possible changes to policies regarding test result distribution should be considered.