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Table 3 Stratified effect estimates of the association between pregnancy loss and rheumatoid arthritis risk

From: Pregnancy loss and the risk of rheumatoid arthritis in Chinese women: findings from the China Kadoorie biobank

 

Pregnancy loss

Ever

1

2

≥3

Per additional

Region

Rural

1.14 (1.06–1.23)*

1.12 (1.02–1.22)*

1.13 (1.01–1.26)*

1.23 (1.09–1.40)*

1.07 (1.03–1.11)*

Urban

1.11 (1.03–1.19)*

1.08 (0.99–1.16)

1.12 (1.03–1.22)*

1.17 (1.06–1.29)*

1.05 (1.02–1.09)*

Income

< 5000

1.10 (0.96–1.27)

1.07 (0.91–1.26)

1.01 (0.82–1.25)

1.29 (1.04–1.61)*

1.06 (1.00–1.14)

5000–19,999

1.10 (1.02–1.19)*

1.06 (0.97–1.15)

1.15 (1.04–1.26)*

1.15 (1.03–1.28)*

1.05 (1.02–1.09)*

≥20,000

1.15 (1.06–1.26)*

1.14 (1.03–1.25)*

1.13 (1.02–1.26)*

1.21 (1.07–1.37)*

1.06 (1.02–1.10)*

MET

< 16.8

1.10 (1.03–1.18)*

1.06 (0.98–1.14)

1.12 (1.03–1.22)*

1.17 (1.07–1.29)*

1.06 (1.02–1.09)*

≥16.8

1.15 (1.06–1.25)*

1.14 (1.04–1.25)*

1.13 (1.01–1.26)*

1.20 (1.06–1.37)*

1.06 (1.02–1.10)*

BMI

< 25

1.15 (1.08–1.23)*

1.13 (1.04–1.22)*

1.14 (1.05–1.25)*

1.23 (1.11–1.36)*

1.07 (1.04–1.10)*

≥25

1.08 (1.00–1.17)

1.04 (0.95–1.15)

1.11 (1.00–1.23)

1.14 (1.01–1.28)*

1.05 (1.01–1.09)*

Smoking

Smoker

0.90 (0.74–1.08)

0.82 (0.66–1.03)

0.90 (0.70–1.16)

1.05 (0.81–1.36)

1.01 (0.93–1.10)

Non-smoker

1.14 (1.08–1.20)*

1.11 (1.05–1.18)*

1.14 (1.07–1.23)*

1.19 (1.10–1.29)*

1.06 (1.03–1.09)*

Alcohol

Alcohol drinker

1.09 (1.00–1.19)

1.06 (0.96–1.18)

1.09 (0.98–1.22)

1.14 (1.01–1.29)*

1.04 (1.00–1.08)*

Non-alcohol drinker

1.13 (1.06–1.21)*

1.10 (1.02–1.19)*

1.14 (1.04–1.24)*

1.21 (1.10–1.34)*

1.06 (1.03–1.10)*

  1. *Statistically significant at the 5% level
  2. BMI Body mass index, MET Metabolic equivalent of task value
  3. Models excludes nulligravid women. Women without pregnancy loss were used as reference
  4. Region: Adjusted for age, province, education, occupation, income, physical activity, body mass index, alcohol use, smoking, gum bleed, hypertension diagnosis, diabetes diagnosis, and livebirths
  5. Income: Adjusted for age, province, region, education, occupation, physical activity, body mass index, alcohol use, smoking, gum bleed, hypertension diagnosis, diabetes diagnosis, and livebirths
  6. Metabolic equivalent of task value: Adjusted for age, province, region, education, occupation, income, body mass index, alcohol, smoking, gum bleed, hypertension diagnosis, diabetes diagnosis, and livebirths
  7. Body mass index: Adjusted for age, province, region, education, occupation, income, physical activity, alcohol use, smoking, gum bleed, hypertension diagnosis, diabetes diagnosis, and livebirths
  8. Smoking: Adjusted for age, province, region, education, occupation, income, physical activity, body mass index, alcohol use, gum bleed, hypertension diagnosis, diabetes diagnosis, and livebirths
  9. Alcohol: Adjusted for age, province, region, education, occupation, income, physical activity, body mass index, smoking, gum bleed, hypertension diagnosis, diabetes diagnosis, and livebirths