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Table 2 Effect estimates of the association between pregnancy loss and rheumatoid arthritis risk

From: Pregnancy loss and the risk of rheumatoid arthritis in Chinese women: findings from the China Kadoorie biobank

 

No. of events

Model 1

Model 2

Pregnancy loss

 Ever vs. never

 

1.28 (1.22–1.34)*

1.12 (1.06–1.18)*

 None

2477

1.00 (reference)

1.00 (reference)

 1

2386

1.19 (1.13–1.26)*

1.09 (1.03–1.16)*

 2

1600

1.31 (1.23–1.40)*

1.13 (1.05–1.20)*

 ≥3

1040

1.44 (1.34–1.55)*

1.19 (1.10–1.28)*

 Per additional

 

1.13 (1.11–1.16)*

1.06 (1.03–1.08)*

Spontaneous abortion

 Ever vs. never

 

1.14 (1.05–1.23)*

1.11 (1.03–1.20)*

 None

6742

1.00 (reference)

1.00 (reference)

 1

593

1.12 (1.03–1.22)*

1.10 (1.01–1.20)*

 2

110

1.05 (0.87–1.27)

1.03 (0.85–1.25)

 ≥3

58

1.58 (1.21–2.06)*

1.50 (1.15–1.96)*

 Per additional

 

1.10 (1.05–1.16)*

1.09 (1.03–1.15)*

Induced abortion

 Ever vs. never

 

1.24 (1.19–1.30)*

1.11 (1.06–1.17)*

 None

3174

1.00 (reference)

1.00 (reference)

 1

2180

1.18 (1.12–1.25)*

1.09 (1.03–1.16)*

 2

1374

1.29 (1.21–1.37)*

1.14 (1.06–1.22)*

 ≥3

775

1.35 (1.25–1.46)*

1.16 (1.06–1.26)*

 Per additional

 

1.12 (1.09–1.14)*

1.05 (1.03–1.08)*

Stillbirth

 Ever vs. never

 

1.16 (1.06–1.28)*

1.07 (0.97–1.18)

 None

7013

1.00 (reference)

1.00 (reference)

 1

392

1.20 (1.09–1.34)*

1.11 (1.00–1.23)

 2

75

1.10 (0.87–1.38)

0.97 (0.77–1.23)

 ≥3

23

0.84 (0.55–1.26)

0.74 (0.49–1.13)

 Per additional

 

1.07 (1.01–1.15)*

1.01 (0.94–1.08)

  1. *Statistically significant at the 5% level
  2. Models for pregnancy loss, spontaneous abortion, induced abortion, and stillbirth excludes nulligravid women
  3. Model 1: unadjusted
  4. Model 2: adjusted for age, province, region, education, occupation, income, metabolic equivalent of task value, body mass index, alcohol use, smoking, gum bleed, hypertension diagnosis, diabetes diagnosis, livebirths, and stillbirths, spontaneous abortion, induced abortion, as appropriate