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Table 3 National estimates of annual incidence rates of IPD and its manifestations among US children aged < 18 Years, in episodes per 100,000 person-years (2001–2018)

From: Incidence of invasive pneumococcal disease in children with commercial insurance or Medicaid coverage in the United States before and after the introduction of 7- and 13-valent pneumococcal conjugate vaccines during 1998–2018

Year

Overall IPD

Meningitis

Bacteremia

Bacteremic pneumonia

All ages

Ages

 < 2

Ages

2–4

Ages

5–17

All ages

Ages

 < 2

Ages

2–4

Ages

5–17

All ages

Ages

 < 2

Ages

2–4

Ages

5–17

All ages

Ages

 < 2

Ages

2–4

Ages

5–17

2001

8.53

49.40

7.19

2.54

1.53

9.56

1.32

0.34

5.09

30.90

3.82

1.41

1.65

7.95

1.94

0.61

2002

5.84

27.00

6.96

2.33

1.30

5.20

1.61

0.63

3.16

17.20

3.74

0.86

1.19

4.06

1.55

0.66

2003

7.43

35.60

8.99

2.74

1.01

3.73

1.24

0.54

4.29

26.00

5.09

0.76

1.78

5.48

2.59

1.03

2004

5.26

23.60

6.49

2.16

0.92

3.29

0.93

0.55

2.62

15.40

2.93

0.58

1.49

4.95

2.63

0.69

2005

5.30

21.70

6.05

2.60

0.87

3.99

0.52

0.47

2.23

11.30

2.48

0.77

1.91

5.96

2.81

1.09

2006

5.06

21.10

7.45

2.04

0.77

2.18

1.37

0.41

2.44

13.00

2.70

0.76

1.66

5.61

3.12

0.72

2007

6.54

32.80

6.98

2.39

1.12

5.09

1.12

0.51

3.40

20.80

2.72

0.88

1.83

6.42

3.08

0.84

2008

6.77

33.00

7.88

2.48

1.13

5.29

1.22

0.47

3.40

21.20

2.82

0.80

2.06

6.17

3.65

1.06

2009

6.91

30.90

7.82

3.01

0.84

4.25

0.62

0.37

3.06

17.10

3.01

0.90

2.75

9.10

4.13

1.45

2010

5.61

21.40

6.25

3.03

0.99

3.41

0.62

0.71

2.43

11.80

2.45

0.99

2.01

5.74

3.05

1.20

2011

4.22

16.10

4.14

2.40

0.73

2.18

0.51

0.56

1.82

9.21

1.87

0.67

1.47

4.04

1.64

1.04

2012

3.97

15.90

4.35

2.05

0.74

3.06

0.65

0.41

1.75

8.41

1.68

0.74

1.34

3.87

1.93

0.82

2013

4.15

17.90

4.19

2.03

0.66

2.06

0.56

0.47

2.17

12.80

1.86

0.61

1.16

2.70

1.68

0.81

2014

3.68

15.10

4.31

1.78

0.67

2.07

0.82

0.41

1.84

9.78

1.88

0.61

1.06

2.87

1.62

0.66

2015

3.69

13.50

5.48

1.76

0.68

2.59

0.66

0.40

1.61

7.24

2.05

0.65

1.19

3.31

2.70

0.52

2016

3.30

11.40

4.62

1.75

0.82

2.81

1.01

0.46

1.37

5.78

1.50

0.66

0.90

2.23

1.88

0.46

2017

3.15

8.79

4.03

2.08

0.74

2.11

0.85

0.50

1.21

3.41

1.72

0.75

0.91

2.23

1.40

0.59

2018

3.23

9.87

4.51

1.92

0.85

2.77

0.91

0.54

1.21

3.92

1.95

0.62

0.98

2.56

1.58

0.60

  1. Abbreviations: IPD Invasive pneumococcal disease, PY Person-years
  2. Note: Incidence rates were adjusted using data from the U.S. Census Bureau, Current Population Survey and Annual Social and Economic Supplements. Census data for each study year were obtained from the US Census Bureau database. Estimates of the July 1st US population by sex, age, and insurance type were calculated for each study year by applying the average proportion of individuals with private and government health insurance for the 0–17 age group across all age-sex categories. IPD incidence rates in the general US pediatric population were calculated by multiplying the incidence rates for each age-sex-insurance type group in the MarketScan data with the proportion of that group in the general US pediatric population, and summing across all groups
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BMC Public Health

ISSN: 1471-2458

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