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Table 2 Multivariable logistic regression model of the association between keratinocyte cancer, hydrochlorothiazide duration, and sun exposure, along with covariates, in north-central Wisconsin adults (N = 999)

From: Hydrochlorothiazide use, sun exposure, and risk of keratinocyte cancer

 

Keratinocyte Cancera

Age (linear years)

0.60 (0.33, 1.09), p = 0.091

Age (spline)

1.96 (1.11, 3.47), p = 0.020

Charlson comorbidity score (points)

1.18 (1.06, 1.32), p = 0.003

Time in cohort before index date (years)

1.00 (0.98, 1.03), p = 0.689

Hydrochlorothiazide duration (years)

1.14 (1.11, 1.18), p < 0.001

 Sun exposure

 High

1.16 (0.71, 1.48), p = 0.563

 Low

–- ref –-

Interaction

1.02 (0.97, 1.09), p = 0.643

 Hydrochlorothiazide duration × High sun exposure

1.16 (1.10, 1.23)

 Hydrochlorothiazide duration × Low sun exposure

1.14 (1.11, 1.18)

  1. aValues are reported as odds ratio (95% confidence interval) and p-value of keratinocyte cancer, relative to the reference category for categorical exposures or a 1-unit increase for continuous exposures