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Table 1 Baseline characteristics of study participants classified as High-Risk by the WHO algorithm and the additional participants classified as high risk when maternal adherence was incorporated into the algorithm

From: Optimizing the World Health Organization algorithm for HIV vertical transmission risk assessment by adding maternal self-reported antiretroviral therapy adherence

Variable

Total

WHO Algorithm High-Risk

Additional High-Risk with the inclusion of maternal adherence

p-value

n = 126

n = 81

n = 45

Age of Children at Enrollment (months)

n = 126

n = 81

n = 45

 

1.57 [0.98;2.91]

1.64 [0.98;3.48]

1.38 [0.98;2.62]

0.277

 Missing values

0 (0%)

0 (0%)

0 (0%)

 

Sex of Children at Birth:

n = 125

n = 80

n = 45

 

 Female

55 (44.0%)

33 (41.2%)

22 (48.9%)

0.523

 Male

70 (56.0%)

47 (58.8%)

23 (51.1%)

 Missing values

1 (0.8%)

1 (1.2%)

0 (0%)

 

Mother WHO HIV Status:

n = 123

n = 78

n = 45

 

 Clinical stage 1/2

115 (93.5%)

72 (92.3%)

43 (95.6%)

1.000

 Clinical stage 3

7 (5.69%)

5 (6.4%)

2 (4.4%)

 Clinical stage 4

1 (0.81%)

1 (1.28%)

0 (0.00%)

 Missing values

3 (2.4%)

3 (3.7%)

0 (0%)

 

Mother Severe Life Events / Health Issues:

n = 115

n = 74

n = 41

 

 No

62 (53.9%)

41 (55.4%)

21 (51.2%)

0.813

 Yes

53 (46.1%)

33 (44.6%)

20 (48.8%)

 Missing values

11 (8.7%)

7 (8.6%)

4 (8.9%)

 

Mother Social Adverse Events:

n = 126

n = 81

n = 45

 

 No

5 (3.97%)

3 (3.7%)

2 (4.4%)

1.000

 Yes

121 (96.0%)

78 (96.3%)

43 (95.6%)

 Missing values

0 (0%)

0 (0%)

0 (0%)

 

Mother Employment Status

n = 123

n = 79

n = 44

 

 Employed

14 (11.4%)

10 (12.7%)

4 (9.1%)

0.763

 Unemployed

109 (88.6%)

69 (87.3%)

40 (90.9%)

Missing values

3 (2.3%)

2 (2.5%)

1 (2.2%)

 

Mother Marital Status

n = 126

n = 81

n = 45

 

 Single

76 (60.3%)

49 (60.5%)

27 (60.0%)

1.000

 Married

47 (37.3%)

30 (37.0%)

17 (37.8%)

 In a relationship, not cohabiting

3 (2.38%)

2 (2.47%)

1 (2.22%)

Missing values

0 (0%)

0 (0%)

0 (0%)

 

Mother Education

n = 126

n = 81

n = 45

 

 No school

3 (2.38%)

2 (2.47%)

1 (2.22%)

0.850

 Primary

44 (34.9%)

26 (32.1%)

18 (40.0%)

 Secondary

74 (58.7%)

49 (60.5%)

25 (55.6%)

 University

5 (3.97%)

4 (4.94%)

1 (2.22%)

Missing values

0 (0%)

0 (0%)

0 (0%)

 
  1. Continuous variables summarized as: median [IQR], and categorical variables as: n (% of subjects within classification group, excluding missing values). The first row of each section shows the number of subjects without missing corresponding information, and last row number and percentage of missing values compared to the total number of subjects. Mother Severe Life Events: Any during the time of the study, including change in employment, separation or relationship break-up, new partner, loss of home or move, death in the family, other. Mother Health Issues: Any during the time of study. Mother Employment status, Marital status and Education asked at enrolment. Mother Social Adverse Events: Unemployed, single status or did not attend high school/university (asked at enrollment). Standard Post-natal prophylaxis: < 6 weeks with one of Zidovudine (AZT) or Nevirapine (NVP)
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