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Table 4 Effect size of sleep duration on albumin in prespecified and exploratory subgroups

From: Association between sleep duration and albumin in US adults: a cross-sectional study of NHANES 2015–2018

sleep duration (h) P for interaction
  7–8 \(\le\) 5 5–6 6–7 8–9 \(>\) 9
sex 0.0418
 male Ref -0.94 (-1.29, -0.60) -0.45 (-0.71, -0.18) 0.09 (-0.12, 0.29) -0.18 (-0.42, 0.06) -0.28 (-0.59, 0.03)  
P value    < 0.0001 0.0011 0.4020 0.1493 0.0739  
 female Ref -0.95 (-1.34, -0.56) -0.47 (-0.77, -0.17) -0.38 (-0.60, -0.15) -0.26 (-0.47, -0.05) -0.58 (-0.86, -0.31)  
P value    < 0.0001 0.0024 0.0009 0.0159  < 0.0001  
race 0.0010
 Mexican American Ref -0.86 (-1.34, -0.39) -0.40 (-0.76, -0.03) -0.19 (-0.48, 0.10) 0.00 (-0.31, 0.32) -0.05 (-0.43, 0.33)  
P value   0.0004 0.0324 0.2015 0.9940 0.7933  
 non-Hispanic white Ref -1.67 (-2.16, -1.17) -0.53 (-0.89, -0.18) -0.15 (-0.41, 0.10) -0.32 (-0.58, -0.05) -0.65 (-1.00, -0.30)  
P value    < 0.0001 0.0033 0.2339 0.0182 0.0003  
 non-Hispanic black Ref 0.05 (-0.40, 0.50) -0.13 (-0.55, 0.29) 0.02 (-0.35, 0.39) -0.02 (-0.43, 0.40) -0.06 (-0.50, 0.38)  
P value   0.8126 0.5405 0.9224 0.9433 0.7906  
 other race Ref -0.02 (-0.67, 0.62) -0.15 (-0.67, 0.37) 0.10 (-0.28, 0.47) -0.18 (-0.59, 0.23) -0.43 (-0.96, 0.10)  
P value   0.9466 0.5760 0.6143 0.3842 0.1095  
marital status 0.0023
 married or living with partner Ref -1.38 (-1.75, -1.01) -0.67 (-0.93, -0.41) -0.23 (-0.42, -0.04) -0.26 (-0.47, -0.06) -0.69 (-0.97, -0.40)  
P value    < 0.0001  < 0.0001 0.0190 0.0116  < 0.0001  
 living alone Ref -0.54 (-0.91, -0.17) -0.06 (-0.38, 0.27) 0.08 (-0.17, 0.33) -0.12 (-0.38, 0.13) -0.17 (-0.46, 0.13)  
P value   0.0047 0.7374 0.5184 0.3454 0.2722  
high cholesterol 0.0177
 yes Ref -1.23 (-1.65, -0.81) -0.61 (-0.93, -0.28) -0.51 (-0.76, -0.26) -0.41 (-0.66, -0.15) -0.83 (-1.15, -0.50)  
P value    < 0.0001 0.0002  < 0.0001 0.0018  < 0.0001  
 no Ref -0.80 (-1.14, -0.46) -0.40 (-0.66, -0.14) 0.05 (-0.14, 0.25) -0.14 (-0.34, 0.07) -0.28 (-0.55, -0.02)  
P value    < 0.0001 0.0023 0.5709 0.1879 0.0367  
AST, IU/L 0.0004
  < 45 Ref -0.83 (-1.10, -0.56) -0.50 (-0.71, -0.30) -0.12 (-0.27, 0.03) -0.21 (-0.37, -0.05) -0.39 (-0.59, -0.18)  
P value    < 0.0001  < 0.0001 0.1197 0.0104 0.0003  
  ≥ 45 Ref -1.51 (-2.77, -0.25) 0.82 (-0.33, 1.97) -0.18 (-1.11, 0.74) -0.20 (-1.18, 0.79) -1.93 (-3.14, -0.73)  
   0.0190 0.1629 0.7016 0.6945 0.0018  
eGFR, ml/min/1.73m2 0.0019
  < 80 Ref -1.00 (-1.40, -0.60) -0.66 (-0.99, -0.33) -0.31 (-0.55, -0.06) -0.40 (-0.66, -0.15) -0.74 (-1.05, -0.43)  
P value    < 0.0001  < 0.0001 0.0134 0.0018  < 0.0001  
 80–120 Ref -0.93 (-1.30, -0.56) -0.48 (-0.75, -0.21) -0.10 (-0.30, 0.10) -0.10 (-0.32, 0.12) -0.02 (-0.32, 0.28)  
P value    < 0.0001 0.0005 0.3282 0.3589 0.8870  
  ≥ 120 Ref -1.23 (-2.17, -0.29) 0.26 (-0.44, 0.96) 0.21 (-0.33, 0.76) 0.02 (-0.55, 0.59) -0.93 (-1.60, -0.26)  
P value   0.0106 0.4718 0.4431 0.9469 0.0064  
  1. Each stratification adjusted for all factors (sex, age, race, marital status, moderate work activity, TP, ALT, AST, Cr, UACR, HS-CRP, GLU, BMI, hypertension, high cholesterol, cancer or malignancy) except the stratification factor itself