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Table 3 aHT drug regimens used in the included care models

From: Community-based care models for arterial hypertension management in non-pregnant adults in sub-Saharan Africa: a literature scoping review and framework for designing chronic services

Author and publication year

Reported pharmacological treatment for aHT

Steyn et al. 1993 [62]

•Men: 25.3% ß-blockers, 22.3% diuretics, 6.4% reserpine-containing preparations

•Women: 43.2% diuretics, 15% reserpine-containing preparations, 14.6% ß-blockers

Oparah et al. 2006 [60]

•Prior to intervention: 33% methyldopa, 11% diuretics, 33% combinations

•Intervention: JNC (Joint National Committee) VII guidelines*, 2004

Ndou et al. 2013 [51]

NR

Khabala et al. 2015 [58]

NR

Marfo et al. 2017 [55]

NR

Nelissen et al. 2018 [61]

NR

Kuria et al. 2018 [54]

NR

Adler et al. 2019 [52]

•At enrolment: 36% used a calcium channel blocker (CCB)

•After 6-months enrolment: 75.9% patients used diuretics and 69.5% were on a CCB. A total of 24.1% were taking only one medication, 32% were taking two medications and over 30% were taking more than two medications

•At 12 m-enrolment: 79.8% were on diuretics, and 71.5% taking a CCB.A total of 23% were taking one medication, 32.6% were taking two medications and over 32% were taking more than two medications

Bolarinwa et al. 2019 [59]

NR

Stephens et al. 2021 [53]

NR

Otieno et al. 2021 [57]

•A total of 74% of patients were on calcium channel blocker, 64% on ACE or ARB and 14% on diuretics. A minority of patients used other treatments

Vedanthan et al. 2021 [56]

•Use of diuretics if SBP \(\ge\) 140 and < 180 OR DBP \(\ge\) 90 and < 110, without edema of legs or dyspnoea on exertion or reduced urine output

•Treatment of hypertension in Diabetes: initial ACE inhibitors. Escalate to ARBs with/without diuretics

  1. *https://www.nhlbi.nih.gov/files/docs/guidelines/jnc7full.pdf