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Table 3 Criteria and sub-criteria (primary care surveillance example)

From: National influenza surveillance systems in five European countries: a qualitative comparative framework based on WHO guidance

Criteria

Sub-criteria

WHO Guidancea

Granularity

Age group

Recommended as a minimum: 0–1, 2–4, 5–14, 15–49, 50–64, 65+ years and ideally additional age strata for under 2 years including 0 to < 6 months, 6 month to < 1 year, 1 to < 2 years

Gender

Where possible data should be extracted by gender

Risk condition

Recommended as a minimum: pregnancy status & presence of chronic pre-existing medical illness(es): chronic respiratory disease, asthma, diabetes, chronic cardiac disease, chronic neurological or neuromuscular disease, haematological disorders, immunodeficiency (including Human Immunodeficiency Virus)

Location

Considered as essential, especially for burden estimation for a given area based on data from sentinel sites

Virology

Types and subtypes of viruses detected during the week

Severity

Additional data to consider: signs and symptoms of illness & patient outcome (death, survival)

Treatment

Exposure to influenza antiviral drugs during the last 14 days? If yes, name of antiviral

Vaccination status

Additional data to consider: Seasonal influenza vaccination status and date of administration

Timing

Frequency

Epidemiological and virological data collected from the sentinel sites should be reported to the national health authorities on a weekly basis

Time period

In temperate climate zones where influenza seasonality is well understood, data collection and reporting should occur at a minimum during the known influenza season and for a short period preceding and following the season

Representativeness

Geographical representativeness

National - sentinel sites should include patients that will appropriately represent the population

Population representativeness

The population served by the sentinel site should be representative of the target age and socioeconomic groups in the population under surveillance

Number of settings

There is no ideal number of sentinel sites in a country. Start small with one or a few sentinel sites and only expand if these function well. Minimal information that should be presented in the weekly report includes number of sentinel sites reporting

Proportion of facilities

Ideally the following analyses can be presented in an annual report: data from the monitoring of the system: proportion of sentinel sites reporting weekly to the national level; and if feasible, the proportion of sentinel sites regularly submitting specimens for laboratory testing

Sampling strategy

Surveillance type

Sentinel surveillance

ARI/ILI definition

An acute respiratory infection with fever ≥38 °C and cough with onset within the last 10 days

Sampling

A systematic approach to case selection that does not leave the choice of cases to test or gather data from up to healthcare providers (other than to determine that the case meets the definition), and that covers different times of the day and different days of the week is likely to be the most pragmatic, while providing reasonably representative data

Test type

Reverse transcriptase-polymerase chain reaction (RT-PCR) is the most sensitive method for detecting influenza virus and is the recommended influenza surveillance assay for laboratories

Communication

In annual report

Yearly surveillance report with surveillance and risk factor data should be produced

In weekly report

Weekly surveillance reports should be produced and made accessible to relevant partners

Delay in release

Reports should provide timely information on influenza activity and types of influenza viruses circulating

Data can be extracted

Whenever feasible, such reports should be available to the public on the national surveillance website

  1. ARI acute respiratory illness, ILI influenza-like illness, RT-PCR reverse transcriptase-polymerase chain reaction.
  2. aFrom WHO global epidemiological surveillance standards for influenza [8] and WHO manual for estimating disease burden associated with seasonal influenza [9]
  3. Further information is included in the additional file.