Table 4 Comorbidity Burden and Adverse Childhood Experiences in ALIVE (N = 653)
From: Adverse childhood experiences and comorbidity in a cohort of people who have injected drugs
Outcomes | Exposure | Model A | Model Ba | Model Cb | |||
|---|---|---|---|---|---|---|---|
Comorbidity Groups | ACEs | OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value |
0 comorbid conditions (ref.) | - | - | - | - | - | - | - |
1–2 comorbid conditions | 0 to 1 ACEs | ref | - | ref | - | - | - |
2 to 4 ACEs | 0.8 (0.6 – 1.2) | .48 | 0.9 (0.6 – 1.3) | .73 | 0.9 (0.6 – 1.3) | .75 | |
5 to 9 ACEs | 0.9 (0.6 – 1.4) | .90 | 1.1 (0.7 – 1.6) | .55 | 1.1 (0.7 – 1.6) | .52 | |
≥ 10 ACEs | 1.1 (0.6 – 1.9) | .68 | 1.0 (0.6 – 1.9) | .75 | 1.1 (0.6 – 1.9) | .70 | |
≥ 3 comorbid conditions | 0 to 1 ACEs | ref | - | ref | - | ref | - |
2 to 4 ACEs | 1.0 (0.6 – 1.8) | .74 | 1.2 (0.7 – 2.1) | .45 | 1.2 (0.7 – 2.2) | .42 | |
5 to 9 ACEs | 1.2 (0.7 – 2.3) | .40 | 1.7 (0.9 – 3.3) | .09 | 1.8 (0.9 – 3.4) | .07 | |
≥ 10 ACEs | 2.7 (1.3 – 6.0) | .01 | 2.7 (1.2 – 6.3) | .01 | 2.9 (1.2 – 6.8) | .01 | |