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Table 5 Antibiotic use in neonates (initial and overall) within 3 days of life

From: Early-onset neonatal sepsis and antibiotic use in Indonesia: a descriptive, cross-sectional study

Antibiotics EOS Non-EOS
(n = 797)
Culture proven
(n = 83)
Culture negative
(n = 112)
Absence of culture facility
(n = 47)
Initial antibiotics
 Ampicillin / Amoxicillin 76 (91.6%) 47 (42.0%) 3 (6.4%) 156 (19.6%)
 Gentamicin 17 (20.5%) 55 (49.1%) 10 (21.3%) 457 (57.3%)
 Amikacin 78 (94.0%) 73 (65.2%) 2 (4.3%) 229 (28.7%)
 Third-generation cephalosporin 27 (32.5%) 26 (23.2%) 41 (87.2%) 181 (22.7%)
Overall antibiotics
 Ampicillin / Amoxicillin 76 (91.6%) 48 (42.9%) 3 (6.4%) 157 (19.7%)
 Penicillin 0 (0.0%) 0 (0.0%) 0 (0.0%) 1 (0.1%)
 Gentamicin 19 (22.9%) 55 (49.1%) 10 (21.3%) 458 (57.5%)
 Netilmicin 39 (47.0%) 8 (7.1%) 0 (0.0%) 12 (1.5%)
 Amikacin 82 (98.8%) 74 (66.1%) 2 (4.3%) 229 (28.7%)
 Ampicillin-Sulbactam 1 (1.2%) 0 (0.0%) 0 (0.0%) 0 (0.0%)
 Amoxicillin-Clavulanic acid 3 (3.6%) 45 (40.2%) 0 (0.0%) 398 (49.9%)
 Piperacillin-tazobactam 3 (3.6%) 28 (25%) 0 (0.0%) 93 (11.4%)
 Imipenem 4 (4.8%) 1 (0.9%) 0 (0.0%) 0 (0.0%)
 Meropenem 20 (24.1%) 9 (8.0%) 0 (0.0%) 16 (2.0%)
 Doripenem 0 (0.0%) 0 (0.0%) 0 (0.0%) 3 (0.4%)
 Third-generation cephalosporin 68 (81.9%) 28 (25.0%) 41 (87.2%) 182 (22.8%)
 Fourth-generation cephalosporin 0 (0.0%) 0 (0.0%) 0 (0.0%) 2 (0.3%)
 Ciprofloxacin 0 (0.0%) 0 (0.0%) 0 (0.0%) 1 (0.1%)
 Vancomycin 1 (1.2%) 0 (0.0%) 3 (6.4%) 3 (0.4%)
 Metronidazole 11 (13.3%) 5 (4.5%) 0 (0.0%) 15 (1.9%)